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  1. Article

    Open Access

    Regulation of eDHFR-tagged proteins with trimethoprim PROTACs

    Temporal control of protein levels in cells and living animals can be used to improve our understanding of protein function. In addition, control of engineered proteins could be used in therapeutic application...

    Jean M. Etersque, Iris K. Lee, Nitika Sharma, Kexiang Xu in Nature Communications (2023)

  2. No Access

    Article

    In vivo detection of hydrogen sulfide in the brain of live mouse: application in neuroinflammation models

    Hydrogen sulfide (H2S) plays important roles in brain pathophysiology. However, nuclear imaging probes for the in vivo detection of brain H2S in living animals have not been developed. Here, we report the first n...

    Bora Nam, Woonghee Lee, Swarbhanu Sarkar in European Journal of Nuclear Medicine and M… (2022)

  3. Article

    Open Access

    In vivo evaluation of the effects of combined boron and gadolinium neutron capture therapy in mouse models

    While boron neutron capture therapy (BNCT) depends primarily on the short flight range of the alpha particles emitted by the boron neutron capture reaction, gadolinium neutron capture therapy (GdNCT) mainly re...

    Woonghee Lee, Kyung Won Kim, Jeong Eun Lim, Swarbhanu Sarkar in Scientific Reports (2022)