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  1. No Access

    Article

    In vivo detection of hydrogen sulfide in the brain of live mouse: application in neuroinflammation models

    Hydrogen sulfide (H2S) plays important roles in brain pathophysiology. However, nuclear imaging probes for the in vivo detection of brain H2S in living animals have not been developed. Here, we report the first n...

    Bora Nam, Woonghee Lee, Swarbhanu Sarkar… in European Journal of Nuclear Medicine and M… (2022)

  2. Article

    Open Access

    In vivo evaluation of the effects of combined boron and gadolinium neutron capture therapy in mouse models

    While boron neutron capture therapy (BNCT) depends primarily on the short flight range of the alpha particles emitted by the boron neutron capture reaction, gadolinium neutron capture therapy (GdNCT) mainly re...

    Woonghee Lee, Kyung Won Kim, Jeong Eun Lim, Swarbhanu Sarkar… in Scientific Reports (2022)

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  3. No Access

    Article

    Structural and Electrical Properties of Nd-Doped (La,Sr)MnO3 Bulk Ceramics

    (La0.7−xNdxSr0.3)MnO3 (x = 0.15–0.3) specimens were prepared using the mixed oxide method. All specimens showed an orthorhombic crystalline structure and exhibited microstructures with sub-μm sized grains and por...

    Chang-Hyun Kim, Myung-Gyu Lee, Jeong-Eun Lim… in Transactions on Electrical and Electronic … (2022)

  4. No Access

    Article

    Lipopolysaccharide-Induced Exosomal miR-146a Is Involved in Altered Expression of Alzheimer’s Risk Genes Via Suppression of TLR4 Signaling

    Repeated exposure to toll-like receptor 4 (TLR4) ligands, such as lipopolysaccharide (LPS), reduces responses of monocytes/macrophages to LPS (LPS/endotoxin tolerance). Microglial exposure to Aβ deposits, a TL...

    Junling Yang, Fiona Malone, Michelle Go, **ghong Kou… in Journal of Molecular Neuroscience (2021)

  5. No Access

    Article

    Catalytic Immunoglobulin Gene Delivery in a Mouse Model of Alzheimer’s Disease: Prophylactic and Therapeutic Applications

    Accumulation of amyloid beta-peptide (Aβ) in the brain is hypothesized to be a causal event leading to dementia in Alzheimer’s disease (AD). Aβ vaccination removes Aβ deposits from the brain. Aβ immunotherapy,...

    **ghong Kou, Junling Yang, Jeong-Eun Lim, Abhinandan Pattanayak… in Molecular Neurobiology (2015)

  6. Article

    Open Access

    TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

    Amyloid plaques, a pathological hallmark of Alzheimer's disease (AD), are accompanied by activated microglia. The role of activated microglia in the pathogenesis of AD remains controversial: either clearing Aβ...

    Min Song, **gJi **, Jeong-Eun Lim, **ghong Kou… in Journal of Neuroinflammation (2011)

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