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Article
The utility of patient-reported outcome measures among patients with myalgic encephalomyelitis/chronic fatigue syndrome
Debilitating fatigue is a core symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); however, the utility of patient-reported symptom outcome measures of fatigue for ME/CFS patients is probl...
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Article
Open AccessTracking post-infectious fatigue in clinic using routine Lab tests
While biomarkers for chronic fatigue syndrome (CFS) are beginning to emerge they typically require a highly specialized clinical laboratory. We hypothesized that subsets of commonly measured laboratory markers...
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Article
Open AccessAssessing the relationship between HIV infection and cervical cancer in Côte d'Ivoire: A case-control study
The association between HIV infection and invasive cervical cancer that has been reported may reflect differential prevalence of human papillomavirus (HPV) infection or uncontrolled confounding. We conducted a...
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Article
Open AccessPreliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr Virus
Acute infectious diseases are typically accompanied by non-specific symptoms including fever, malaise, irritability and somnolence that usually resolve on recovery. However, in some individuals these symptoms ...
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Article
Open AccessChronic Fatigue Syndrome – A clinically empirical approach to its definition and study
The lack of standardized criteria for defining chronic fatigue syndrome (CFS) has constrained research. The objective of this study was to apply the 1994 CFS criteria by standardized reproducible criteria.
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Article
Open AccessThe economic impact of chronic fatigue syndrome
Chronic fatigue syndrome (CFS) is a chronic incapacitating illness that affects between 400,000 and 800,000 Americans. Despite the disabling nature of this illness, scant research has addressed the economic im...
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Protocol
Molecular Characterization of Human Papillomaviruses by PCR and In Situ Hybridization
The goal of early detection and screening is the diagnosis and treatment of cancer before it spreads beyond the organ of origin, perhaps even in its preinvasive state. Unfortunately, available early detection ...
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Article
Open AccessIdentification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution
Chronic fatigue syndrome (CFS) is defined by symptoms and disability, has no confirmatory physical signs or characteristic laboratory abnormalities, and the etiology and pathophysiology remain unknown. Difficu...
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Article
Open AccessBioelectronic DNA detection of human papillomaviruses using eSensor™: a model system for detection of multiple pathogens
We used human papillomaviruses (HPV) as a model system to evaluate the utility of a nucleic acid, hybridization-based bioelectronic DNA detection platform (eSensor™) in identifying multiple pathogens.
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Protocol
Detection of Human Papillomaviruses by Polymerase Chain Reaction and In Situ Hybridization
The clinical utility of human papillomavirus (HPV) testing continues to be the focus of much debate. The clear epidemiologic link of HPV infection with the development of cervical intraepithelial neoplasia and...