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  1. Article

    Open Access

    The LIN28B/TGF-β/TGFBI feedback loop promotes cell migration and tumour initiation potential in cholangiocarcinoma

    Cholangiocarcinoma (CCA), a lethal malignancy of the biliary epithelium, is the second most common primary liver cancer. The poor prognosis of CCA is due to the high rate of tumour invasion and distant metasta...

    Nattapong Puthdee, Sira Sriswasdi, Trairak Pisitkun… in Cancer Gene Therapy (2022)

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    Article

    DHODH modulates transcriptional elongation in the neural crest and melanoma

    Transgenic zebrafish carrying the human oncogene BRAF(V600E), the most common mutation in melanoma patients, provide a convenient model for melanoma. Two papers from Leonard Zon and colleagues demonstrate the pot...

    Richard Mark White, Jennifer Cech, Sutheera Ratanasirintrawoot, Charles Y. Lin… in Nature (2011)

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    Article

    Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

    Methods for reprogramming human cells are unable to prospectively distinguish bona fide induced pluripotent stem (iPS) cells from partially reprogrammed cells. Using live imaging to monitor cell fate, Chan et al....

    Elayne M Chan, Sutheera Ratanasirintrawoot, In-Hyun Park… in Nature Biotechnology (2009)