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  1. No Access

    Protocol

    Microfluidic Coaxial Bioprinting of Hollow, Standalone, and Perfusable Vascular Conduits

    Three-dimensional bioprinting represents promising approach for fabricating standalone and perfusable vascular conduits using biocompatible materials. Here we describe a step-by-step method by using a multicha...

    Sushila Maharjan, Jacqueline Jialu He, Li Lv, Di Wang… in Vascular Tissue Engineering (2022)

  2. Article

    Open Access

    Engineering multifunctional bactericidal nanofibers for abdominal hernia repair

    The engineering of multifunctional surgical bactericidal nanofibers with inherent suitable mechanical and biological properties, through facile and cheap fabrication technology, is a great challenge. Moreover,...

    Samson Afewerki, Nicole Bassous, Samarah Vargas Harb… in Communications Biology (2021)

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  3. No Access

    Article

    Local Delivery of CTGF siRNA with Poly(sorbitol-co-PEI) Reduces Scar Contraction in Cutaneous Wound Healing

    Healing process in scarring inevitably produces a considerable amount of non-organized dense collagen-rich matrix called scar thus impairing the native structure of skin. Connective tissue growth factor (CTGF)...

    Ki-Hyun Cho, Bijay Singh, Sushila Maharjan… in Tissue Engineering and Regenerative Medici… (2017)

  4. No Access

    Article

    Gene therapy for bone tissue engineering

    Gene therapy holds a great promise and has been extensively investigated to improve bone formation and regeneration therapies in bone tissue engineering. A variety of osteogenic genes can be delivered by combi...

    Young-Dong Kim, Prasad Pofali, Tae-Eun Park… in Tissue Engineering and Regenerative Medici… (2016)

  5. No Access

    Article

    Biosynthesis of the nargenicin A1 pyrrole moiety from Nocardia sp. CS682

    A number of structurally diverse natural products harboring pyrrole moieties possess a wide range of biological activities. Studies on biosynthesis of pyrrole ring have shown that pyrrole moieties are derived ...

    Sushila Maharjan, Niraj Aryal, Saurabh Bhattarai… in Applied Microbiology and Biotechnology (2012)

  6. No Access

    Article

    Metabolic engineering of Streptomyces venezuelae for malonyl-CoA biosynthesis to enhance heterologous production of polyketides

    Using metabolic engineering, we developed Streptomyces venezuelae YJ028 as an efficient heterologous host to increase the malonyl-CoA pool to be directed towards enhanced production of various polyketides. To pro...

    Sushila Maharjan, Je Won Park, Yeo Joon Yoon, Hei Chan Lee… in Biotechnology Letters (2010)

  7. No Access

    Article

    Heterologous expression of metK1-sp and afsR-sp in Streptomyces venezuelae for the production of pikromycin

    Two regulator genes, metK1-sp and afsR-sp, from Streptomyces peucetius ATCC 27952 were heterologously expressed in S. venezuelae ATCC 15439, to produce 14-membered pikromycin antibiotics. The production of pikrom...

    Sushila Maharjan, Tae-** Oh, Hei Chan Lee, Jae Kyung Sohng in Biotechnology Letters (2008)