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  1. No Access

    Article

    Duodenal HFE expression and hepcidin levels determine body iron homeostasis: modulation by genetic diversity and dietary iron availability

    HFE affects the interaction of transferrin bound iron with transferrin receptors (TfR) thereby modulating iron uptake. To study genetically determined differences in HFE expression we examined individual HFE l...

    Susanne Ludwiczek, Igor Theurl, Erika Artner-Dworzak… in Journal of Molecular Medicine (2004)

  2. No Access

    Article

    The Macrophage: A Cellular Factory at the Interphase Between Iron and Immunity for the Control of Infections

    Igor Theurl, Gernot Fritsche, Susanne Ludwiczek, Katja Garimorth… in Biometals (2005)

  3. No Access

    Article

    Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1

    Hereditary hemochromatosis and transfusional iron overload are frequent clinical conditions associated with progressive iron accumulation in parenchymal tissues, leading to eventual organ failure. We have disc...

    Susanne Ludwiczek, Igor Theurl, Martina U Muckenthaler, Martin Jakab… in Nature Medicine (2007)

  4. No Access

    Article

    Short term protective effects of iron in a murine model of ischemia/reperfusion

    The role of iron in the pathogenesis of cardio-vascular disorders is still controversial. We studied the effects of iron perturbations on myocardial injury upon temporary ischemia/reperfusion. C57BL/6J male mi...

    Bernhard Metzler, Johannes Jehle, Igor Theurl, Susanne Ludwiczek, Peter Obrist… in BioMetals (2007)