12 Result(s)
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Surendra K Prajapati
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Open AccessRepeat controlled human Plasmodium falciparum infections delay bloodstream patency and reduce symptoms
Resistance to clinical malaria takes years to develop even in hyperendemic regions and sterilizing immunity has rarely been observed. To evaluate the maturation of the host response against controlled repeat e...
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Open AccessAuthor Correction: The transcriptome of circulating sexually committed Plasmodium falciparum ring stage parasites forecasts malaria transmission potential
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Open AccessThe transcriptome of circulating sexually committed Plasmodium falciparum ring stage parasites forecasts malaria transmission potential
Malaria is spread by the transmission of sexual stage parasites, called gametocytes. However, with Plasmodium falciparum, gametocytes can only be detected in peripheral blood when they are mature and transmissibl...
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Open AccessPublisher Correction: Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessPlasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes
Plasmodium sexual differentiation is required for malaria transmission, yet much remains unknown about its regulation. Here, we quantify early gametocyte-committed ring (gc-ring) stage, P. falciparum parasites in...
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Open AccessMolecular analysis of reticulocyte binding protein-2 gene in Plasmodium vivax isolates from India
Plasmodium vivax reticulocyte binding protein-2 (PvRBP-2) is a promising candidate for development of vaccine against parasite. DNA sequence polymorphism in pvrbp-2 which may hamper the vaccine development progra...
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Open AccessThe repertoire diversity of the Plasmodium falciparum stevor multigene family in complicated and uncomplicated malaria in India
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Open AccessPlasmodium vivax lineages: geographical distribution, tandem repeat polymorphism, and phylogenetic relationship
Multi-drug resistance and severe/complicated cases are the emerging phenotypes of vivax malaria, which may deteriorate current anti-malarial control measures. The emergence of these phenotypes could be associa...
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Open AccessAntigenic repertoire of Plasmodium vivax transmission-blocking vaccine candidates from the Indian subcontinent
Genetic polymorphism is an inevitable component of a multistage infectious organism, such as the malaria parasite. By means of genetic polymorphism, parasite opts particular polymorph and reveals survival adva...
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Open AccessMolecular epidemiology of Plasmodium vivax anti-folate resistance in India
Sulphadoxine and pyrimethamine are anti-folate drugs that show synergistic anti-malarial effect. Point mutations in dihydrofolate reductase (dhfr) and dihydropteorate synthatase (dhps) cause anti-folate drug resi...
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Open AccessGenetic structure of Plasmodium falciparum field isolates in eastern and north-eastern India
Molecular techniques have facilitated the studies on genetic diversity of Plasmodium species particularly from field isolates collected directly from patients. The msp-1 and msp-2 are highly polymorphic markers a...
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Open AccessAllelic dimorphism of Plasmodium vivax gam-1 in the Indian subcontinent
Genetic polymorphism is an inevitable component of a complex organism especially in multistage infectious organisms such as malaria parasites. Understanding the population genetic structure of the parasites wo...
