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  1. No Access

    Article

    Insight into Mechanisms of Cellular Uptake of Lipid Nanoparticles and Intracellular Release of Small RNAs

    Understanding mechanisms of cellular uptake and intracellular release would enable better design of nanocarriers for delivery of nucleic acids such as siRNA and microRNA (miRNA).

    Bo Yu, **nmei Wang, Chenguang Zhou, Lesheng Teng, Wei Ren… in Pharmaceutical Research (2014)

  2. Article

    Open Access

    Target delivery of MYCN siRNA by folate-nanoliposomes delivery system in a metastatic neuroblastoma model

    Folate-nanoliposomes delivery system has emerged recently as a specific and safety delivery method and gradually used as the carrier of a variety kinds of drugs including compounds, plasmids and siRNAs.

    Qiqi Zhu, Chen Feng, Weiwei Liao, Yan Zhang, Suoqin Tang in Cancer Cell International (2013)

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  3. No Access

    Article

    Silencing of the MYCN gene by siRNA delivered by folate receptor-targeted liposomes in LA-N-5 cells

    MYCN amplification is highly associated with malignancy and correlates with poor prognosis in patients with neuroblastoma.

    Chen Feng, Tianyou Wang, Ruihong Tang, Jianwen Wang… in Pediatric Surgery International (2010)

  4. No Access

    Article

    All-trans retinoic acid is capable of inducing folate receptor β expression in KG-1 cells

    The high expression of folate receptor (FR) on cancer cells might be a potential target for cancer therapy. In this study, the FR-β expression and the modulation effect of all-trans retinoic acid (ATRA) in a n...

    Ying Xu, Tianyou Wang, Ruihong Tang, Suoqin Tang in Tumor Biology (2010)