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Open AccessAnalysis of treatment pattern of anti-dementia medications in newly diagnosed Alzheimer’s dementia using OMOP CDM
Anti-dementia medications are widely prescribed to patients with Alzheimer’s dementia (AD) in South Korea. This study investigated the pattern of medical management in newly diagnosed patients with AD using a ...
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Open AccessAssociation of body mass index and COPD exacerbation among patients with chronic bronchitis
Chronic obstructive pulmonary disease (COPD) patients with a body mass index (BMI) < 25 kg/m2 are prone to develop adverse event of pharmacological treatment for frequent exacerbation. As chronic bronchitis (CB) ...
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Article
Open AccessCoffee consumption and diabetic retinopathy in adults with diabetes mellitus
We aimed to evaluate the association between the prevalence of diabetic retinopathy (DR) and coffee consumption in a Korean population. This cross-sectional study was based on data from the 2008–2011 Korean Na...
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Open AccessPrediction of newborn’s body mass index using nationwide multicenter ultrasound data: a machine-learning study
This study introduced machine learning approaches to predict newborn’s body mass index (BMI) based on ultrasound measures and maternal/delivery information.
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Open AccessA 3D-CNN model with CT-based parametric response map** for classifying COPD subjects
Chronic obstructive pulmonary disease (COPD) is a respiratory disorder involving abnormalities of lung parenchymal morphology with different severities. COPD is assessed by pulmonary-function tests and compute...
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Article
Emphysema quantification using low-dose computed tomography with deep learning–based kernel conversion comparison
This study determined the effect of dose reduction and kernel selection on quantifying emphysema using low-dose computed tomography (LDCT) and evaluated the efficiency of a deep learning–based kernel conversio...
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Article
Effectiveness of sleep surgery versus a mandibular advancement device for obstructive sleep apnea in terms of nocturnal cardiac autonomic activity
Sleep surgery and mandibular advancement devices (MAD) are treatments for obstructive sleep apnea (OSA), but their comparative efficacy remains unclear. We compared their efficacy using various parameters.
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Open AccessLong-term exposure to PM10 and NO2 in relation to lung function and imaging phenotypes in a COPD cohort
Ambient air pollution can contribute to the development and exacerbation of COPD. However, the influence of air pollution on objective COPD phenotypes, especially from imaging, is not well studied. We investig...
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Open AccessQuantitative CT-based structural alterations of segmental airways in cement dust-exposed subjects
Dust exposure has been reported as a risk factor of pulmonary disease, leading to alterations of segmental airways and parenchymal lungs. This study aims to investigate alterations of quantitative computed tom...
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Article
Methylation quantitative trait loci analysis in Korean exposome study
Environmental exposure and genotype variation influence DNA methylation. Studies on the effects of genotype variation were performed mainly on European ancestries. We analyzed the genetic effects on cord blood...
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Open AccessNocturnal heart rate variability may be useful for determining the efficacy of mandibular advancement devices for obstructive sleep apnea
A mandibular advancement device (MAD) is recommended as an alternative therapy for obstructive sleep apnea (OSA), which effectively reduces the collapsibility of the upper airway during sleep by advancing the ...
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Article
Perilesional emphysema as a predictor of risk of complications from computed tomography-guided transthoracic lung biopsy
This study evaluated whether or not patterns of emphysema and their qualitative and quantitative severity can predict the risk of complications with post-computed tomography (CT)-guided transthoracic lung biop...
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Open AccessComputed tomography-derived area and density of pectoralis muscle associated disease severity and longitudinal changes in chronic obstructive pulmonary disease: a case control study
Muscle wasting is associated with prognosis in patients with chronic obstructive pulmonary disease (COPD). The cross-sectional area of skeletal muscles on computed tomography (CT) could serve as a method to ev...
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Open AccessGenome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults
Ambient air pollution is associated with numerous adverse health outcomes, but the underlying mechanisms are not well understood; epigenetic effects including altered DNA methylation could play a role. To eval...
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Effect of dietary patterns on the blood/urine concentration of the selected toxic metals (Cd, Hg, Pb) in Korean children
This study was aimed to examine the association the blood/urinary concentration of toxic metal (Hg, Pb, and Cd) with children’s dietary patterns. This cross-sectional study included 1026 school children aged 8...
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Open AccessSerial blood eosinophils and clinical outcome in patients with chronic obstructive pulmonary disease
Blood eosinophils have been suggested as a potential biomarker in chronic obstructive pulmonary disease (COPD), and their stability over time has been investigated in a few studies. However, the association be...
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Article
Effect of prenatal antioxidant intake on infants’ respiratory infection is modified by a CD14 polymorphism
Prenatal maternal diet may influence disease susceptibility in offspring with specific genetic backgrounds. We hypothesized that interactions between prenatal antioxidant intake and polymorphisms in immunity g...
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Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Open AccessModification of additive effect between vitamins and ETS on childhood asthma risk according to GSTP1 polymorphism : a cross -sectional study
Asthma is characterized by airway inflammation, and bronchial airways are particularly susceptible to oxidant-induced tissue damage.
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Article
Low tropospheric wind measurement with Mie Doppler Lidar
A double edge Mie Doppler lidar at 1064 nm was developed in Hefei, China in 2005 for low tropospheric wind measurement. Intercomparison experiments with a wind profiler and a wiresonde were held. Intercomparis...