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Article
Open AccessComparison of digital and analog [68Ga]Ga-PSMA-11 PET/CT for detecting post-prostatectomy biochemical recurrence in prostate cancer patients: a prospective study
Digital positron emission tomography/computed tomography (PET/CT) has shown enhanced sensitivity and spatial resolution compared with analog PET/CT. The present study compared the diagnostic performance of dig...
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Article
Open AccessEvaluation of machine learning approach for surgical results of Ahmed valve implantation in patients with glaucoma
Ahmed valve implantation demonstrated an increasing proportion in glaucoma surgery, but predicting the successful maintenance of target intraocular pressure remains a challenging task. This study aimed to eval...
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Article
Open AccessComparative estimation of the effects of antihypertensive medications on schizophrenia occurrence: a multinational observational cohort study
The association between antihypertensive medication and schizophrenia has received increasing attention; however, evidence of the impact of antihypertensive medication on subsequent schizophrenia based on larg...
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Article
Open AccessChromophoric cerium oxide nanoparticle-loaded sucking disk-type strip sensor for optical measurement of glucose in tear fluid
Noninvasive monitoring of tear glucose levels can be convenient for patients to manage their diabetes mellitus. However, there are issues with monitoring tear glucose levels, such as the invasiveness of some m...
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Article
Open AccessDifferent effects of menopausal hormone therapy on non-alcoholic fatty liver disease based on the route of estrogen administration
The effects of menopausal hormone therapy (MHT) on non-alcoholic fatty liver disease (NAFLD) were compared based on the route of estrogen administration. The study included 368 postmenopausal women who receive...
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Article
Open AccessNanoarchitectured conjugates targeting angiogenesis: investigating heparin-taurocholate acid conjugates (LHT7) as an advanced anti-angiogenic therapy for brain tumor treatment
Glioblastoma is a highly malignant brain tumor associated with poor prognosis. Conventional therapeutic approaches have limitations due to their toxic effects on normal tissue and the development of tumor cell...
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Article
Open AccessUse of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in children
Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood. Although it requires timely detection and intervention, existing continuous performance tests (CPTs)...
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Article
Nest-relief behaviors and usage of call types in the Kentish plover (Charadrius alexandrinus)
In bi-parental species, breeding pairs cooperate to regulate incubation duration through nest-relief behavior, using vocal signals to communicate when exchanging incubation duties. To better understand this be...
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Article
Open AccessPhotosensitizing deep-seated cancer cells with photoprotein-conjugated upconversion nanoparticles
To resolve the problem of target specificity and light transmission to deep-seated tissues in photodynamic therapy (PDT), we report a cancer cell-targeted photosensitizer using photoprotein-conjugated upconver...
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Article
Open AccessInhibition of DAMP actions in the tumoral microenvironment using lactoferrin-glycyrrhizin conjugate for glioblastoma therapy
High-mobility group box-1 (HMGB1) released from the tumor microenvironment plays a pivotal role in the tumor progression. HMGB1 serves as a damaged-associated molecular pattern (DAMP) that induces tumor angiog...
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Article
Open AccessA local water molecular-heating strategy for near-infrared long-lifetime imaging-guided photothermal therapy of glioblastoma
Owing to the strong absorption of water in the near-infrared (NIR) region near 1.0 μm, this wavelength is considered unsuitable as an imaging and analytical signal in biological environments. However, 1.0 μm N...
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Article
Open AccessMachine learning-based prediction model for postoperative delirium in non-cardiac surgery
Postoperative delirium is a common complication that is distressing. This study aimed to demonstrate a prediction model for delirium.
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Article
Comparison of goserelin and leuprorelin for ovarian protection during chemotherapy in young patients with breast cancer
Although different gonadotropin-releasing hormone (GnRH) agonists may have different effects, their effect of ovarian protection during chemotherapy for breast cancer has not been compared. This study aimed to co...
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Article
Open AccessAssociations of reproductive factors with incidence of myocardial infarction and ischemic stroke in postmenopausal women: a cohort study
To assess the association between the reproductive factors of age at menarche, age at menopause, and reproductive span and the incidence of myocardial infarction (MI) and ischemic stroke (IS).
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Article
Open AccessLong-term methylphenidate use for children and adolescents with attention deficit hyperactivity disorder and risk for depression, conduct disorder, and psychotic disorder: a nationwide longitudinal cohort study in South Korea
Methylphenidate (MPH) is the most frequently prescribed medication for the treatment of attention deficit hyperactivity disorder (ADHD). However, the safety of its long-term use remain unclear. In particular, ...
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Article
Why was he murdered? The first report of the motive for conspecific killing in a flock of captive tree sparrows (Passer montanus) through direct video surveillance
In animal societies, conspecific killing is the most extreme way in which individuals resolve conflicts and is rarely reported in the literature. The reasons for such behavior are unclear because the majority ...
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Article
Local pattern growth of carbon nanomaterials on flexible polyimide films using laser scribing and its sensor application
A gas detection system that monitors harmful gases is critical for the preservation of the global environment and human health. Owing to the increased interest in flexible devices for various types of wearable...
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Article
Diagnostic value of [68 Ga]Ga-DOTA-labeled-somatostatin analogue PET/MRI for detecting liver metastasis in patients with neuroendocrine tumors: a systematic review and meta-analysis
To determine the diagnostic value of [68 Ga]Ga-DOTA-labeled-somatostatin analogue ([68 Ga]Ga-DOTA-SSA) PET/MRI for detecting liver metastasis in patients with neuroendocrine tumor (NET) and to compare it with [68
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Article
Open AccessHormone therapy and the decreased risk of dementia in women with depression: a population-based cohort study
The literature has shown depression to be associated with an increased risk of dementia. In addition, hormone therapy can be a responsive treatment option for a certain type of depression. In this study, we ex...
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Article
Open AccessQuality of life and patient satisfaction with raloxifene/cholecalciferol combination therapy in postmenopausal women
This study was performed to evaluate quality of life (QOL) and patient satisfaction with raloxifene/cholecalciferol combination therapy in postmenopausal women with low bone mass. This multicenter, prospective...
