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  1. Article

    Open Access

    Distinct effects of cholesterol profile components on amyloid and vascular burdens

    Cholesterol plays important roles in β-amyloid (Aβ) metabolism and atherosclerosis. However, the relationships of plasma cholesterol levels with Aβ and cerebral small vessel disease (CSVD) burdens are not full...

    Sung Hoon Kang, Hee** Yoo, Bo Kyoung Cheon, Yu Hyun Park in Alzheimer's Research & Therapy (2023)

  2. Article

    Open Access

    Independent effect of Aβ burden on cognitive impairment in patients with small subcortical infarction

    The effect of amyloid-β (Aβ) on cognitive impairment in patients with small subcortical infarction remains controversial, although a growing body of evidence shows a substantial overlap between Alzheimer’s dis...

    Sung Hoon Kang, Minwoong Kang, Jung Hoon Han in Alzheimer's Research & Therapy (2023)

  3. Article

    Open Access

    Different effects of cardiometabolic syndrome on brain age in relation to gender and ethnicity

    A growing body of evidence shows differences in the prevalence of cardiometabolic syndrome (CMS) and dementia based on gender and ethnicity. However, there is a paucity of information about ethnic- and gender-...

    Sung Hoon Kang, Mengting Liu, Gilsoon Park, Sharon Y. Kim in Alzheimer's Research & Therapy (2023)

  4. Article

    Open Access

    Gender-specific relationship between thigh muscle and fat mass and brain amyloid-β positivity

    The relationship of specific body composition in the thighs and brain amyloid-beta (Aβ) deposition remained unclear, although there were growing evidence that higher muscle and fat mass in thighs had a protect...

    Sung Hoon Kang, Kyung Hyun Lee, Yoosoo Chang in Alzheimer's Research & Therapy (2022)

  5. Article

    Open Access

    Decreased visual acuity is related to thinner cortex in cognitively normal adults: cross-sectional, single-center cohort study

    Decreased visual acuity (VA) is reported to be a risk factor for dementia. However, the association between VA and cortical thickness has not been established. We investigated the association between VA and co...

    Gyule Han, Ji Sun Kim, Yu Hyun Park, Sung Hoon Kang in Alzheimer's Research & Therapy (2022)

  6. Article

    Open Access

    Identifying novel genetic variants for brain amyloid deposition: a genome-wide association study in the Korean population

    Genome-wide association studies (GWAS) have identified a number of genetic variants for Alzheimer’s disease (AD). However, most GWAS were conducted in individuals of European ancestry, and non-European populat...

    Hang-Rai Kim, Sang-Hyuk Jung, Jaeho Kim, Hyemin Jang in Alzheimer's Research & Therapy (2021)

  7. Article

    Open Access

    Differential effects of risk factors on the cognitive trajectory of early- and late-onset Alzheimer’s disease

    Although few studies have shown that risk factors for Alzheimer’s disease (AD) are associated with cognitive decline in AD, not much is known whether the impact of risk factors differs between early-onset AD (...

    Jaeho Kim, Sook-Young Woo, Seonwoo Kim, Hyemin Jang in Alzheimer's Research & Therapy (2021)

  8. Article

    Open Access

    Cognitive trajectories of patients with focal ß-amyloid deposition

    The presence of ß-amyloid (Aß) in the brain can be identified using amyloid PET. In clinical practice, the amyloid PET is interpreted based on dichotomous visual rating, which renders focal Aß accumulation be ...

    Si Eun Kim, Byungju Lee, Hyemin Jang, Juhee Chin in Alzheimer's Research & Therapy (2021)

  9. Article

    Open Access

    Optical coherence tomography angiography as a potential screening tool for cerebral small vessel diseases

    The retina and the brain share anatomic, embryologic, and physiologic characteristics. Therefore, retinal imaging in patients with brain disorders has been of significant interest. Using optical coherence tomo...

    Ju-Yeun Lee, Jun Pyo Kim, Hyemin Jang, Jaeho Kim in Alzheimer's Research & Therapy (2020)