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Article
Open AccessDevelopment of a multidisciplinary medication management program in nursing homes: protocol for a randomized controlled trial
Polypharmacy and the use of potentially inappropriate medications are common among nursing home residents and are associated with negative outcomes. Although deprescribing has been proposed as a way to curtail...
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Article
Increased risk of incident gout in patients with hyperthyroidism: a nationwide retrospective cohort study
Previous studies have reported that thyroid dysfunction is associated with increased serum uric acid levels; however, the relationship between hyperthyroidism and incidence of clinical manifestations of gout h...
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Article
Open AccessReal-world incidence and risk factors of bortezomib-related cardiovascular adverse events in patients with multiple myeloma
Although most studies on the cardiovascular toxicity of proteasome inhibitors have focused on carfilzomib, the risk of cardiotoxicity associated with bortezomib remains controversial. This study aimed to evalu...
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Article
Open AccessDevelopment of a claims-based risk-scoring model to predict emergency department visits in older patients receiving anti-neoplastic therapy
This study developed and validated a risk-scoring model, with a particular emphasis on medication-related factors, to predict emergency department (ED) visits among older Korean adults (aged 65 and older) unde...
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Article
Open AccessDevelopment and validation of a machine learning-based fall-related injury risk prediction model using nationwide claims database in Korean community-dwelling older population
Falls impact over 25% of older adults annually, making fall prevention a critical public health focus. We aimed to develop and validate a machine learning-based prediction model for serious fall-related injuri...
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Open AccessMachine learning-based prediction model for emergency department visits using prescription information in community-dwelling non-cancer older adults
Older adults are more likely to require emergency department (ED) visits than others, which might be attributed to their medication use. Being able to predict the likelihood of an ED visit using prescription i...
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Article
Nationwide-incidence and trends of fibromyalgia in South Korea: a population-based study
Reports of the incidence of fibromyalgia (FM) in Asia are uncommon. Therefore, this study used nationwide representative data to investigate the age- and sex-specific incidence and annual trends of FM in South...
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Article
Open AccessNovel innovative computer-based test (Inno-CBT) item types for national licensing examinations for health care professionals
An effective test mechanism to evaluate clinical knowledge and skills of the entry-level healthcare professionals is important for providing clinical competency and improving patient care. This study aimed to ...
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Article
Open AccessPotentially inappropriate medication use as predictors of hospitalization for residents in nursing home
Hospitalization of nursing home (NH) residents impose a significant healthcare burden. However, there is still a lack of information regarding the risk of hospitalization from inappropriate prescribing in NH r...
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Article
Open AccessSystemic evaluation of the risk of reoperations in pediatric populations with exotropia and esotropia: nested case–control study
The study aimed to assess the risk of reoperations for strabismus in the pediatric population and to identify high-risk groups. This was a nationwide population-based study that used data from the Korean Natio...
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Article
Analysis of Anti-Angiogenesis-Related Adverse Events Associated with Vascular Endothelial Growth Factor Receptor-Tyrosine Kinase Inhibitors (VEGFR-TKIs) in Patients with Metastatic Renal Cell Carcinoma
Limited studies have evaluated anti-angiogenesis-related adverse events involving oral vascular endothelial growth factor receptor-tyrosine kinase inhibitors (VEGFR-TKIs) in metastatic renal cell carcinoma usi...
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Article
Prognostic Significance of the Severity of Immune-Related Adverse Events in Advanced Cancer Patients Treated with PD-1/PD-L1 Inhibitors: A Real-World Data Analysis
There is limited evidence regarding immune-related adverse events (irAEs) in Asian cancer patients treated with antibodies directed against programmed cell death-1 (PD-1) or programmed cell death-ligand 1 (PD-...
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Article
Open AccessGenetic causal inference between amblyopia and perinatal factors
Amblyopia is a common visual disorder that causes significant vision problems globally. Most non-ocular risk factors for amblyopia are closely related to the intrauterine environment, and are strongly influenc...
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Article
Open AccessA measure to estimate the risk of imported COVID-19 cases and its application for evaluating travel-related control measures
High connectivity between nations facilitates the spread of infectious diseases. We introduce an improved measure to estimate the risk of COVID-19 importation. The measure was applied to identify the effective...
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Article
Risk Factors for Intravenous Propacetamol-Induced Blood Pressure Drop in the Neurointensive Care Unit: A Retrospective Observational Study
Intravenous propacetamol is commonly used to control fever and pain in neurocritically ill patients in whom oral administration is often difficult. However, several studies reported that intravenous propacetam...
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Article
Nationwide incidence of myotonic dystrophy type 1 and the status of multi-organ involvement
This study aimed to investigate the incidence of myotonic dystrophy type 1 (DM1) and the status of multi-organ involvement.
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Article
Open AccessPrevalence of potentially inappropriate medications based on the STOPPFrail criteria in frail older patients with limited life expectancy: a cross-sectional study
The recently developed Screening Tool of Older Persons' Prescriptions in Frail adults with a limited life expectancy (STOPPFrail) criteria can be helpful for screening medications (PIMs), but it is yet to be w...
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Article
Open AccessAllergic conjunctivitis increases the likelihood of undergoing eyelid incision surgery in pediatric and adolescent patients
The global prevalence of allergic diseases has increased dramatically in recent decades. From a global health perspective, they have been considered as a major chronic disease, and the related social burden ha...
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Article
Efficacy and Safety of Clinically Driven Low-Dose Treatment with Direct Oral Anticoagulants in Asians with Atrial Fibrillation: a Systematic Review and Meta-analysis
Although clinically driven low-dose (CDLD) treatment with direct oral anticoagulants (DOACs) is frequently administered to Asian patients with atrial fibrillation, clinical evidence confirming its efficacy rem...
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Article
Open AccessInadequate housing and pulmonary tuberculosis: a systematic review
Tuberculosis (TB) is a global health issue that has long threatened and continues to threaten human health. While previous studies are important in the search for a cure for TB, to eradicate the disease it is ...
