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  1. Article

    Open Access

    Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy

    Oleanolic acid has been used only as a subsidiary agent in cosmetic products. The aim of the study is to show the effect of oleanolic acid as an active ingredient for the alleviation of wrinkles in humans and ...

    Joo Young An, Hee Seon Yang, Na Rae Park, Tae-sung Koo… in Nanoscale Research Letters (2020)

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  2. Article

    Open Access

    Preparation and evaluation of poly(2-hydroxyethyl aspartamide)-hexadecylamine-iron oxide for MR imaging of lymph nodes

    The purpose of this study was to synthesize biocompatible poly(2-hydroxyethyl aspartamide)–C16-iron oxide (PHEA-C16-iron oxide) nanoparticles and to evaluate their efficacy as a contrast agent for magnetic resona...

    Dae Chul Ha, Ha Young Lee, Yeo Won Son, Soon Hong Yuk… in Nanoscale Research Letters (2014)

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  3. Article

    Open Access

    Gd(III)-DOTA-modified sonosensitive liposomes for ultrasound-triggered release and MR imaging

    Ultrasound-sensitive (sonosensitive) liposomes for tumor targeting have been studied in order to increase the antitumor efficacy of drugs and decrease the associated severe side effects. Liposomal contrast age...

    Suk Hyun Jung, Kyunga Na, Seul A Lee, Sun Hang Cho… in Nanoscale Research Letters (2012)

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  4. No Access

    Article

    Multi-core vesicle nanoparticles for controlled delivery of protein drug

    The Pluronic/poly(ethylene glycol) composite nanoparticles (NPs) composed of Pluronic F-68, liquid poly(ethylene glycol) (PEG; molecular weight, 400) and human growth hormone (hGH) were stabilized with the ves...

    Soon Hong Yuk, Keun Sang Oh, Seung Ki Kim, ** Ho Lee… in Macromolecular Research (2012)

  5. Article

    Open Access

    Biocompatible Polyhydroxyethylaspartamide-based Micelles with Gadolinium for MRI Contrast Agents

    Biocompatible poly-[N-(2-hydroxyethyl)-d,l-aspartamide]-methoxypoly(ethyleneglycol)-hexadecylamine (PHEA-mPEG-C16) conjugated with 1,4,7,10-tetraazacyclododecan-1,4,7,10-tetraacetic acid-gadolinium (DOTA-Gd) via ...

    Sang Young Jeong, Hyo Jeong Kim, Byung-Kook Kwak… in Nanoscale Research Letters (2010)

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  6. No Access

    Article

    The effect of gamma irradiation on PLGA and release behavior of BCNU from PLGA wafer

    The objectives of this study were to investigate the influence of gamma irradiation for sterilization on poly(D,L-lactide-co-glycolide) (PLGA) with different molecular weight and the effect of gamma irradiation o...

    ** Soo Lee, Gang Soo Chae, Gilson Khang, Moon Suk Kim… in Macromolecular Research (2003)

  7. No Access

    Article

    Local drug delivery system using biodegradable polymers

    For last five years, we are develo** the novel local drug delivery devices using biodegradable polymers, especially polylactide (PLA) and poly(D,L-lactide-co-glycolide) (PLGA) due to its relatively good biocomp...

    Gilson Khang, John M. Rhee, Je Kyo Jeong, Jeong Sik Lee… in Macromolecular Research (2003)

  8. No Access

    Article

    Preparation of 5-fluorouracil-loaded poly(L-lactide-co-glycolide) wafer and evaluation ofin vitro release behavior

    The controlled delivery of anticancer agents using biodegradable polymeric implant has been developed to solve the problem of penetration of blood brain barrier and severe systemic toxicity. This study was per...

    ** Soo Lee, Gang Soo Chae, Tae Kun An, Gilson Khang… in Macromolecular Research (2003)

  9. No Access

    Article

    Thermocontrol of solute permeation across polymer membrane composed of poly(N,N-dimethylaminoethyl methacrylate) and its copolymers

    Polymer membranes composed ofN,N-dimethylaminoethyl methacrylate (DMAEMA) and acrylamide (AAm) (or ethyl acrylamide (EAAm)) were prepared to demonstrate the thermocontrol of solute permeation. Poly DMEMA has a lo...

    Soon Hong Yuk, Sun Hang Cho in Biotechnology and Bioprocess Engineering (2001)

  10. No Access

    Article

    Electric Current-Sensitive Drug Delivery Systems Using Sodium Alginate/Polyacrylic Acid Composites

    Soon Hong Yuk, Sun Hang Cho, Hai Bang Lee in Pharmaceutical Research (1992)