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Article
A cyclin D1-negative mantle cell lymphoma with an IGL-CCND2 translocation that relapsed with blastoid morphology and aggressive clinical behavior
Mantle cell lymphoma (MCL) is a B cell neoplasm characterized by cyclin D1 overexpression; its prognosis is poor, especially when it exhibits a blastoid morphology. Cyclin D1-negative MCL is rare, and its path...
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Article
Clinical efficacy and safety of arbekacin for high-risk infections in patients with hematological malignancies
We performed a clinical trial to investigate the efficacy and safety of arbekacin (ABK), a unique aminoglycoside with activity against methicillin-resistant Staphylococcus aureus (MRSA), in patients with hematolo...
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Article
Dose-intensified CHOP with rituximab (R-Double-CHOP) followed by consolidation high-dose chemotherapies for patients with advanced diffuse large B-cell lymphoma
Even after the advent of rituximab, clinical outcomes of conventional immuno-chemotherapy for high-risk diffuse large B-cell lymphoma (DLBCL) remain unsatisfactory. We retrospectively evaluated the efficacy an...
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Article
The European Treatment and Outcome Study score is associated with clinical outcomes and treatment response following European LeukemiaNet 2013 recommendations in chronic-phase chronic myeloid leukemia
The introduction of tyrosine kinase inhibitors has dramatically improved outcomes for many patients with chronic myeloid leukemia (CML), but some cases are resistant to this treatment. To compare the prognosti...
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Article
Erratum to: An effective salvage treatment using ifosfamide, etoposide, cytarabine, dexamethasone, and rituximab (R-IVAD) for patients with relapsed or refractory aggressive B-cell lymphoma
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Article
Charlson Comorbidity Index is an independent prognostic factor among elderly patients with diffuse large B-cell lymphoma
The clinical outcome for elderly patients with diffuse large B-cell lymphoma (DLBCL) has improved. However, the management of elderly patients with cancer is frequently complicated by their coexisting disorder...
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Article
An effective salvage treatment using ifosfamide, etoposide, cytarabine, dexamethasone, and rituximab (R-IVAD) for patients with relapsed or refractory aggressive B-cell lymphoma
We evaluated the efficacy and toxicity of a new salvage regimen, consisting of rituximab (375 mg/m2, day 1), ifosfamide (1500 mg/m2 on days 3–7), etoposide (150 mg/m2, days 3–5), cytarabine (100 mg/m2, days 3–5) ...
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Article
A case of aggressive myeloma recognized shortly after the remission following high-dose chemotherapy with autologous peripheral blood stem cell transplantation
A 45-year-old woman was referred to our hospital with acute renal failure and pyrexia. In August 2005, the patient was diagnosed with IgA-λ type multiple myeloma with chromosome 13 deletion, and received three...
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Article
Feasibility and eligibility of retreatment with rabbit anti-T lymphocyte globulin for aplastic anemia previously treated with horse anti-thymocyte globulin
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Article
Graft-versus-tumor effect after reduced-intensity allogeneic hematopoietic stem cell transplantation in a patient with advanced colon cancer
A 27-year-old man with advanced colon cancer that was resistant to conventional chemoradiotherapies was treated with reduced-intensity allogeneic peripheral blood stem cell transplantation (PBSCT). After obtai...
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Article
Supplemental utility of nested PCR for the pathological diagnosis of disseminated trichosporonosis
Disseminated trichosporonosis is known to be a severe opportunistic mycosis and has a high mortality rate. In autopsy cases, it is often difficult to diagnose as trichosporonosis because the causative Trichosporo...
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Article
Usefulness of magnifying endoscopic evaluation of the terminal ileum for a patient with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
The gastrointestinal tract is one of the common targets of acute graft-versus-host disease (GVHD), but accurate diagnosis is difficult because of the nonspecific nature of complicated diseases and the lack of ...
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Article
Avascular necrosis in the femoral head secondary to bone marrow infarction in a patient with graft-versus-host disease after unrelated bone marrow transplantation
We previously reported a case of bone marrow infarction attributable to acute graft-versus-host disease (GVHD) in a patient with acute lymphoblastic leukemia after unrelated bone marrow transplantation (BMT). ...
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Chapter and Conference Paper
Antileukemic Effects of Interleukin 2 after Allogeneic Bone Marrow Transplantation in AKR/J Mice
AKR/J mice show a high incidence of spontaneous virus-induced T cell leukemiaat the age of 6-12 months, and a number of factors are involved in the high susceptibility to leukemiadevelopment. The present study...
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Chapter and Conference Paper
Cytokine Gene Expression in Peripheral Blood Mononuclear Cells after Allogeneic Blood Stem Cell Transplantation
GVHD is one of the major complications of allogeneic bone marrow transplantation (allo BMT). Although it is mainly caused by donor T lymphocytes, cytokines play a central role in the regulation of immune respo...