Pulmonary Disease
Pathology, Radiology, Bronchoscopy
Book
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Association with human papilloma virus 6/11 and 16/18
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Large-cell carcinoma is usually peripheral, large, lobulated and/or well marginated, heterogeneously enhancing mass with central necrosis (central necrosis may be absent if size is small).
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Small-cell carcinoma usually arises from the main or proximal lobar bronchi and is located centrally in vast majority of patients who present with hilar or mediastinal mass.
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Bronchial obstruction can lead to atelectasis or recurrent pneumonia of the affected lung/lobe/segment. The iceberg sign refers to a small portion of the tumor visible within the bronchial lumen compared to bulk ...
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Primary salivary gland–type tumors of the lung are rare neoplasms that arise from the submucosal glands of central airways. Four histologic types are identified (two of which are extremely rare).
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Benign tumors of the lung which arise from the bronchial mucous glands and usually present as a solitary lung nodule.
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Endobronchial nodule with segmental, lobar, or total lung collapse (early presentation). The Golden S sign refers to central obstructive right hilar tumor with right upper lobe atelectasis, which may be due to SC...
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Poorer prognosis with early metastasis.
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Respiratory bronchiolitis and follicular bronchiolitis are characterzed by ill-defined centrilobular nodules, while mosaicism and air-trap** are the imaging hallmark of obliterative bronchiolitis.
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Classified as a subtype of large-cell carcinoma, large-cell neuroendocrine carcinoma arises from Kulchitsky cells of the bronchus similar to other neuroendocrine tumors of the lung (sixth decade, smokers).
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Rare subtype of poorly differentiated NSCLC (0.1–0.4%) with overall poor prognosis compared to other NSCLCs, which have a sarcoma-like histology characterized by spindled, pleomorphic cells.
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Primary mesenchymal tumors of the lung are rare. These arise from cells of mesodermal origin in the lungs that develop into bone, cartilage, or other connective tissues, such as blood vessels, adipose tissue, ...
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International Association for the Study of Lung Cancer (IASLC)/the American Thoracic Society (ATS)/the European Respiratory Society (ERS) classification followed...
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Most common pleural tumors are metastatic from the thorax or elsewhere (often adenocarcinomas). Primary pleural tumors are rare – two most common are malignant mesothelioma (almost uniformly fatal) and solitar...
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Chronic obstructive pulmonary disease or COPD refers to a group of chronic inflammatory lung diseases that cause airflow obstruction from the lungs, and most commonly include emphysema. chronic bronchitis and ...
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Interstitial lung disease with lung inflammation and/or fibrosis caused by entities such as hypersensitivity pneumonitis, sarcoidosis, pulmonary Langerhans Cell histiocytosis, and eosinophilic pneumonia are di...
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Acute onset bilateral lung infiltrates on CXR and hypoxemia (ALI = pAO2/F1O2 ≤ 300 mm Hg to severe form ARDS = pAO2/F1O2 ≤ 200 mm Hg) without clinical evidence of left atrial hypertension (or PCWP <18 mm Hg).
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Pulmonary toxicity can occur therapeutic agents as well as recreational drug abuse. Common imaging patterns of lung injury due to therapeutic drugs are highlighted in a table, and lung injury patterns from rec...
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Mean PA pressure > 25 mm Hg at rest or > 35 mm Hg with exercise; high pulmonary vascular resistance.