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Article
Open AccessSoft, full Wheatstone bridge 3D pressure sensors for cardiovascular monitoring
Variations in parameters associated with the ambient environment can introduce noise in soft, body-worn sensors. For example, many piezoresistive pressure sensors exhibit a high degree of sensitivity to fluctu...
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Chapter and Conference Paper
Automated Marker-Less Patient-to-Preoperative Medical Image Registration Approach Using RGB-D Images and Facial Landmarks for Potential Use in Computed-Aided Surgical Navigation of the Paranasal Sinus
Paranasal sinus surgery is an established treatment option for chronic rhinosinusitis. Because this surgery is performed inside the nasal cavity, where critical anatomical structures, such as optic nerves and ...
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Article
Catalytic multicomponent reaction involving a ketyl-type radical
The development of new strategies and concepts towards the synthetic utilization of carbonyl compounds is of pivotal relevance. Nevertheless, the generation of ketyl radicals requires relatively harsh conditio...
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Article
Robust Path Following Control Via Command-Filtered Backstep** Scheme
This paper presents a robust path following control law that enables a fixed-wing UAV to track a reference path under the wind disturbance. The proposed path following control law combines the kinematic contro...
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Article
Open AccessPellino1 promotes chronic inflammatory skin disease via keratinocyte hyperproliferation and induction of the T helper 17 response
Psoriasis is one of the most common immune-mediated chronic inflammatory skin diseases. However, little is known about the molecular mechanism underlying the immunological circuits that maintain innate and ada...
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Article
Open AccessCreatine and taurine mixtures alleviate depressive-like behaviour in Drosophila melanogaster and mice via regulating Akt and ERK/BDNF pathways
We investigated the antidepressant effect of creatine (CRE) and taurine (TAU) mixtures on behavioural changes and biomarkers in stress-induced depression in Drosophila melanogaster and a mouse model. Following CR...
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Article
Open AccessStructural basis for lamin assembly at the molecular level
Nuclear structure and function are governed by lamins, which are intermediate filaments that mostly consist of α-helices. Different lamin assembly models have been proposed based on low resolution and fragment...
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Article
Open AccessPellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks
DNA double-strand break (DSB) signaling and repair are critical for genome integrity. They rely on highly coordinated processes including posttranslational modifications of proteins. Here we show that Pellino1...
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Article
Open AccessSmall-molecule inhibitor of HlyU attenuates virulence of Vibrio species
Increasing antibiotic resistance has led to the development of new strategies to combat bacterial infection. Anti-virulence strategies that impair virulence of bacterial pathogens are one of the novel approach...
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Article
Controlled production of monodisperse polycaprolactone microspheres using flow-focusing microfluidic device
These days, biodegradable microsphere polymers have been attracting increasing interest as a cosmetic injectable filler. Particularly, polycaprolactone (PCL) microspheres are well known for their safety and lo...
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Article
Open AccessOncogenic microtubule hyperacetylation through BEX4-mediated sirtuin 2 inhibition
Five brain-expressed X-linked (BEX) gene members (BEX1–5) are arranged in tandem on chromosome X, and are highly conserved across diverse species. However, little is known about the function and role of BEX. T...
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Article
Open AccessClearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients
Here, we demonstrate that electroporation-enhanced immunization with a rationally designed HPV DNA vaccine (GX-188E), preferentially targeting HPV antigens to dendritic cells, elicits a significant E6/E7-speci...
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Article
Bus signal priority strategies for Multi-directional bus routes
Though the Bus Signal Priority (BSP) system is well known as an effective way to enhance the service quality of bus travel, the effectiveness of the BSP system significantly depends on the traffic and network ...
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Article
Development of a test strip reader for a lateral flow membrane-based immunochromatographic assay
A low-cost, simple strip reader system using a linear movement mechanism of CD-ROM deck has been developed to characterize a lateral flow membrane-based immunochromatographic assay. The test strip reader was a...
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Chapter and Conference Paper
Squeezing Micropumps for Elastomer Microchips; Picoliter-Handling Capability
We have developed a squeezing micropump for elastomeric micropumps, which is featured by capabilities of bi-directional pum**, highly reproducible and ultra-small-volume handling down to picoliters.
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Article
Post-Electrophoresis Capillary Scanner for Detecting DNA Sequencing Reaction Products
A post-electrophoresis capillary scanning technique has been developed and its feasibility as a high-throughput DNA sequencing method has been demonstrated. In this method, capillary gel electrophoresis separa...
