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  1. Article

    Open Access

    Radical thioesterification via nickel-catalysed sensitized electron transfer

    Multi-catalytic reaction modes have attracted widespread attention in synthetic chemistry. The merger of nickel catalysis with photoredox catalysis has offered a powerful platform for synthesis of molecules wi...

    Huamin Wang, Zhao Liu, Ankita Das, Peter Bellotti, Sebastian Megow… in Nature Synthesis (2023)

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  2. No Access

    Article

    Photochemical single-step synthesis of β-amino acid derivatives from alkenes and (hetero)arenes

    β-Amino acids are frequently found as important components in numerous biologically active molecules, drugs and natural products. In particular, they are broadly utilized in the construction of bioactive pepti...

    Guangying Tan, Mowpriya Das, Hyeyun Keum, Peter Bellotti… in Nature Chemistry (2022)

  3. No Access

    Article

    Catalytic multicomponent reaction involving a ketyl-type radical

    The development of new strategies and concepts towards the synthetic utilization of carbonyl compounds is of pivotal relevance. Nevertheless, the generation of ketyl radicals requires relatively harsh conditio...

    Huan-Ming Huang, Peter Bellotti, Suhyeon Kim, **aolong Zhang… in Nature Synthesis (2022)

  4. Article

    Open Access

    Facile access to fused 2D/3D rings via intermolecular cascade dearomative [2 + 2] cycloaddition/rearrangement reactions of quinolines with alkenes

    Hybrid fused two-dimensional/three-dimensional (2D/3D) rings are important pharmacophores in drugs owing to their unique structural and physicochemical properties. Preparation of these strained ring systems of...

    Jiajia Ma, Shuming Chen, Peter Bellotti, Tobias Wagener… in Nature Catalysis (2022)

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  5. No Access

    Article

    Allylic C(sp3)–H arylation of olefins via ternary catalysis

    Transforming C(sp3)–H bonds efficiently and selectively into C(sp3)–C(sp3) or C(sp3)–X bonds is a highly relevant task. The direct arylation of allylic C(sp3)–H bonds provides an elegant method for the formation ...

    Huan-Ming Huang, Peter Bellotti, Pan-Pan Chen, Kendall N. Houk… in Nature Synthesis (2022)

  6. No Access

    Article

    Recent advances in the chemistry and applications of N-heterocyclic carbenes

    N-Heterocyclic carbenes, despite being isolated and characterized three decades ago, still capture scientists’ interest as versatile, modular and strongly coordinating moieties. In the last decade, driven by t...

    Peter Bellotti, Maximilian Koy, Matthew N. Hopkinson… in Nature Reviews Chemistry (2021)

  7. No Access

    Article

    N-Heterocyclic carbenes as tunable ligands for catalytic metal surfaces

    Heterogeneous catalysts represent the backbone of many industrial processes and thus have a considerable societal impact. The active sites of these heterogeneous catalysts are often metal surfaces, which consi...

    Maximilian Koy, Peter Bellotti, Mowpriya Das, Frank Glorius in Nature Catalysis (2021)

  8. No Access

    Article

    Bifunctional reagents in organic synthesis

    Developments in synthetic chemistry are increasingly driven by improvements in the selectivity and sustainability of transformations. Bifunctional reagents, either as dual coupling partners or as a coupling pa...

    Huan-Ming Huang, Peter Bellotti, Jiajia Ma, Toryn Dalton… in Nature Reviews Chemistry (2021)