40 Result(s)
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Article
An enzymocytochemical study of alkaline phos-phatase isoenzymes in gastric cancer — Light and electron microscopic observations
By using light and electron microscopic cytochemical technique, the activities and distributions of AP isoenzymes in gastric cancers and benign gastric diseases were examined. The results showed; Nagao, Regan ...
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Abstracts of Articles
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Article
Expression of ras gene in experimental hepatocarcinogenesis in tree shrews
Objective: In order to investigate the relationship between the expression of ras gene and the development of hepatocellular carcinoma (HCC). Materials and Methods: The experimental tree shrews were divided into ...
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Protective effects and mechanism of total coptis alkaloids on A β25–35 induced learning and memory dysfunction in rats
To observe the effect of total coptis alkaloids (TCA) on β-amyloid peptide (A β25–35) induced learning and memory dysfunction in rats, and to explore its mechanism.
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Roles for negative cell regulator 14-3-3σ in control of MDM2 activities
The 14-3-3σ, upregulated by p53 in response to DNA damage, can have a positive-feedback impact driving p53 activities and is a human cancer epithelial marker downregulated in various tumors. However, the precise ...
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Open AccessCell type specificity of female lung cancer associated with sulfur dioxide from air pollutants in Taiwan: An ecological study
Many studies have examined the association between air pollutants (including sulfur dioxide [SO2], carbon monoxide [CO], nitrogen dioxide [NO2], nitric oxide [NO], ozone [O3], and particulate matter < 10 μm [PM10
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NF-κB inducing kinase (NIK) modulates melanoma tumorigenesis by regulating expression of pro-survival factors through the β-catenin pathway
Nuclear factor-κB (NF-κB) inducing kinase (NIK) is a MAP3K that regulates the activation of NF-κB. NIK is often highly expressed in tumor cells, including melanoma, but the significance of this in melanoma pro...
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Open AccessApplication of a nanotechnology antimicrobial spray to prevent lower urinary tract infection: a multicenter urology trial
Catheter-associated urinary tract infection (CAUTI) is a common nosocomial device-associated infection. It is now recognized that the high infection rates were caused by the formation of biofilm on the surface...
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Promoting an Inclusive Approach to Benefit Sharing: Expanding the Scope of the CBD?
The Convention on Biological Diversity (CBD) is a major international agreement to ensure the conservation of biological diversity, the sustainable use of various components of biological diversity, and fair a...
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Open AccessEvidence for cervical cancer mortality with screening program in Taiwan, 1981–2010: age-period-cohort model
Cervical cancer is the most common cancer experienced by women worldwide; however, screening techniques are very effective for reducing the risk of death. The national cervical cancer screening program was imp...
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Association of ZNF644, GRM6, and CTNND2 genes with high myopia in the Han Chinese population: Jiangsu Eye Study
High myopia is a common visual disorder in the world. The ZNF644, GRM6, and CTNND2 genes are expressed in the retina. This study aims to investigate the associations of these genes with high myopia in Han Chinese...
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Psychological Treatments for Chronic Pain in East and Southeast Asia: A Systematic Review
Psychological treatments are recognised as generally effective for chronic pain. However, little is known about the evidence for psychological treatments for chronic pain in Asia.
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Distinct roles of ASIC3 and TRPV1 receptors in electroacupuncture-induced segmental and systemic analgesia
Previous studies have demonstrated the effects of different afferent fibers on electroacupuncture (EA)-induced analgesia. However, contributions of functional receptors expressed on afferent fibers to the EA a...
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Open AccessMulti-region and single-cell sequencing reveal variable genomic heterogeneity in rectal cancer
Colorectal cancer is a heterogeneous group of malignancies with complex molecular subtypes. While colon cancer has been widely investigated, studies on rectal cancer are very limited. Here, we performed multi-...
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Open AccessAssociation and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population
Nicotine dependence (ND) is a worldwide health problem. Numerous genetic studies have demonstrated a significant association of variants in nicotinic acetylcholine receptors (nAChRs) with smoking behaviors. Ho...
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Open AccessIntratumoral heterogeneity of EGFR-activating mutations in advanced NSCLC patients at the single-cell level
Intratumoral epidermal growth factor receptor (EGFR) mutational heterogeneity is yet controversial in non-small cell lung cancer (NSCLC) patients. Single-cell analysis provides the genetic profile of single cance...
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Open AccessRelationship between psychological health and quality of life of people affected by leprosy in the community in Guangdong province, China: a cross-sectional study
This paper investigates the relationship between psychological health and quality of life (QOL) of people affected by leprosy (PAL) living in a community in Guangdong province, China.
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Open AccessSOX9 drives the epithelial–mesenchymal transition in non-small-cell lung cancer through the Wnt/β-catenin pathway
The distant metastasis of cancer cells is a risk factor for tumor lethality and poor prognosis in non-small-cell lung carcinoma (NSCLC). Increased SOX9 expression has been associated with clinical stage and po...
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Open AccessHeterogeneous components of lung adenocarcinomas confer distinct EGFR mutation and PD-L1 expression
Lung adenocarcinoma (LAC) is composed of lepidic, papillary, mucinous, micropapillary and solid components in its parenchyma. Complex responses to therapeutics result from intratumoral heterogeneity. However, ...
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Open AccessLaparoscopic-based perivascular renal sympathetic nerve denervation: a feasibility study in a porcine model
This study aims to evaluate the effects and safety of laparoscopic-based perivascular renal sympathetic nerve denervation (RDN) in a porcine model fed a high-fat diet.
