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Brain health in preterm infants: importance of early-life pain and analgesia exposure

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  1. Article

    Open Access

    Maternal milk in the NICU: An everyday intervention to improve brain development

    Stephanie L. Merhar, Steven P. Miller in Pediatric Research (2024)

  2. Article

    Open Access

    The Effect of Size and Asymmetry at Birth on Brain Injury and Neurodevelopmental Outcomes in Congenital Heart Disease

    Poor and asymmetric fetal growth have been associated with neonatal brain injury (BI) and worse neurodevelopmental outcomes (NDO) in the growth-restricted population due to placental insufficiency. We tested t...

    Shalin A. Parekh, Stephany M. Cox, A. James Barkovich, Vann Chau in Pediatric Cardiology (2022)

  3. Article

    The influence of pain, agitation, and their management on the immature brain

    Preterm infants are exposed to frequent painful procedures and agitating stimuli over the many weeks of their hospitalization in the neonatal intensive care unit (NICU). The adverse neurobiological impact of p...

    Christopher McPherson, Steven P. Miller, Mohamed El-Dib in Pediatric Research (2020)

  4. Article

    Postnatal polyunsaturated fatty acids associated with larger preterm brain tissue volumes and better outcomes

    Human studies investigating the link between postnatal polyunsaturated fatty acids and preterm brain growth are limited, despite emerging evidence of potential effects on outcomes.

    Daphne Kamino, Colin Studholme, Mengyuan Liu, Vann Chau in Pediatric Research (2018)

  5. Article

    Early postnatal docosahexaenoic acid levels and improved preterm brain development

    Preterm birth has a dramatic impact on polyunsaturated fatty acid exposures for the develo** brain. This study examined the association between postnatal fatty acid levels and measures of brain injury and de...

    Emily W. Y. Tam, Vann Chau, A. James Barkovich, Donna M. Ferriero in Pediatric Research (2016)

  6. Article

    Society for Pediatric Research 2014 Presidential Address: the test of our progress

    Steven P. Miller in Pediatric Research (2014)

  7. Article

    Evolution of pattern of injury and quantitative MRI on days 1 and 3 in term newborns with hypoxic–ischemic encephalopathy

    Brain injury in term neonatal hypoxic–ischemic encephalopathy (HIE) emerges on magnetic resonance imaging (MRI) by day 3. This study aimed to address the relationship of MRI, diffusion tensor imaging (DTI), an...

    Dawn Gano, Vann Chau, Kenneth J. Poskitt, Alan Hill, Elke Roland in Pediatric Research (2013)

  8. Article

    Single-ventricle anatomy predicts delayed microstructural brain development

    Term newborns with congenital heart disease (CHD) show delayed brain development as early as the third trimester, especially in single-ventricle physiology (SVP). Mechanisms causing delayed brain development i...

    Viyeka Sethi, Sarah Tabbutt, Anastasia Dimitropoulos, Kevin C. Harris in Pediatric Research (2013)

  9. Article

    Postnatal infection is associated with widespread abnormalities of brain development in premature newborns

    Infection is a risk factor for adverse neurodevelopmental outcome in preterm newborns. Our objective was to characterize the association of postnatal infection with adverse microstructural and metabolic brain ...

    Vann Chau, Rollin Brant, Kenneth J. Poskitt, Emily W.Y. Tam in Pediatric Research (2012)

  10. Article

    Magnetoencephalography Reveals Slowing of Resting Peak Oscillatory Frequency in Children Born Very Preterm

    Resting cortical activity is characterized by a distinct spectral peak in the alpha frequency range. Slowing of this oscillatory peak toward the upper theta-band has been associated with a variety of neurologi...

    Sam M Doesburg, Urs Ribary, Anthony T Herdman, Alexander Moiseev in Pediatric Research (2011)

  11. Article

    Cerebellar Development in the Preterm Neonate: Effect of Supratentorial Brain Injury

    Cerebellar injury has been increasingly recognized as a complication of preterm birth, with decreased cerebellar volumes seen on follow-up neuroimaging. A cohort of 38 preterm newborns, including 14 with two s...

    Emily W Y Tam, Donna M Ferriero, Duan Xu, Jeffrey I Berman in Pediatric Research (2009)

  12. Article

    White Matter Injury in Term Newborns With Neonatal Encephalopathy

    White matter injury (WMI) is the characteristic pattern of brain injury detected on magnetic resonance imaging in the premature newborn. Focal noncystic WMI is increasingly recognized in populations of term ne...

    Amanda M Li, Vann Chau, Kenneth J Poskitt, Michael A Sargent in Pediatric Research (2009)

  13. Article

    Neonatal Encephalopathy: Association of Cytokines with MR Spectroscopy and Outcome

    In term neonatal encephalopathy, little is known about the relationship between early inflammatory markers, neonatal brain injury, and long-term neurodevelopmental outcome. Our goal was to determine whether ne...

    Agnes I Bartha, Audrey Foster-Barber, Steven P Miller in Pediatric Research (2004)

  14. Article

    Predictors of 30-Month Outcome after Perinatal Depression: Role of Proton MRS and Socioeconomic Factors

    The objective was to determine in infants with perinatal depression whether the relative concentrations of N-acetylaspartate and lactate in the neonatal period are associated with (1) neurodevelopmental outcome a...

    Steven P Miller, Nancy Newton, Donna M Ferriero, J Colin Partridge in Pediatric Research (2002)