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  1. Article

    Open Access

    COPD Self-Management: A Patient–Physician Perspective

    This article is co-authored by five patients living with chronic obstructive pulmonary disease (COPD), and a primary care physician who has over 30 years of clinical experience and is involved in educating hea...

    Michael Coakley, Michael Drohan, Elaine Bruce, Sylvia Hughes in Pulmonary Therapy (2024)

  2. Article

    Open Access

    IMP2ART: development of a multi-level programme theory integrating the COM-B model and the iPARIHS framework, to enhance implementation of supported self-management of asthma in primary care

    Supported asthma self-management, incorporating an asthma action plan and annual clinical review, has been recommended by UK/global guidelines for over three decades. However, implementation remains poor, as o...

    Liz Steed, Jessica Sheringham, Kirstie McClatchey in Implementation Science Communications (2023)

  3. Article

    Open Access

    A Charter to Fundamentally Change the Role of Oral Corticosteroids in the Management of Asthma

    Asthma affects 339 million people worldwide, with an estimated 5–10% experiencing severe asthma. In emergency settings, oral corticosteroids (OCS) can be lifesaving, but acute and long-term treatment can produ...

    John Haughney, Tonya Winders, Steve Holmes, Pascal Chanez in Advances in Therapy (2023)

  4. Article

    Open Access

    IMPlementing IMProved Asthma self-management as RouTine (IMP2ART) in primary care: study protocol for a cluster randomised controlled implementation trial

    Asthma is a common long-term condition and major public health problem. Supported self-management for asthma that includes a written personalised asthma action plan, supported by regular professional review, r...

    Kirstie McClatchey, Vicky Hammersley, Liz Steed, Jessica Sheringham, Viv Marsh in Trials (2023)

  5. Article

    Open Access

    A Renewed Charter: Key Principles to Improve Patient Care in Severe Asthma

    Asthma is a heterogenous respiratory disease, usually associated with chronic airway inflammation and hyper-responsiveness, which affects an estimated 339 million people worldwide. Severe asthma affects approx...

    Andrew Menzies-Gow, David J. Jackson, Mona Al-Ahmad in Advances in Therapy (2022)

  6. Article

    Open Access

    Comparison of COPD primary care in England, Scotland, Wales, and Northern Ireland

    Currently the National Asthma and COPD audit programme (NACAP) only undertakes audit of COPD primary care in Wales due to its near complete data coverage. We aimed to determine if the quality of COPD primary c...

    Philip W. Stone, Katherine Hickman, Steve Holmes in npj Primary Care Respiratory Medicine (2022)

  7. Article

    Open Access

    Develo** a theoretically informed education programme within the context of a complex implementation strategy in UK primary care: an exemplar from the IMP2ART trial

    IMPlementing IMProved Asthma self-management as RouTine (IMP2ART) is a programme of work develo** and evaluating a strategy for implementing supported asthma self-management in UK primary care. The strategy enc...

    Kirstie McClatchey, Viv Marsh, Liz Steed, Steve Holmes, Stephanie J. C. Taylor in Trials (2022)

  8. Article

    Open Access

    Global Quality Standard for Identification and Management of Severe Asthma

    Severe asthma is a debilitating, life-threatening disease associated with substantial global morbidity, mortality, and health care resource utilization. Patients may not receive guideline-directed medical care...

    John Haughney, Tonya A. Winders, Steve Holmes, Pascal Chanez in Advances in Therapy (2020)

  9. Article

    Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery

    Mice engineered to express the entire human variable immunoglobulin region enable rapid isolation of high-affinity antibodies specific for antigens of interest.

    E-Chiang Lee, Qi Liang, Hanif Ali, Luke Bayliss, Alastair Beasley in Nature Biotechnology (2014)

  10. Article

    Open Access

    Novel study design to assess the utility of the copd assessment test in a primary care setting

    The quality of a consultation provided by a physician can have a profound impact on the quality of care and patient engagement in treatment decisions. When the COPD Assessment Test (CAT) was developed, one of ...

    Kevin Gruffydd-Jones, Helen Marsden, Steve Holmes in BMC Medical Research Methodology (2013)

  11. Article

    Book reviews

    Antibody Engineering — A Practical Approach.

    Steve Holmes in Heredity (1997)