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Article
Open AccessCOPD Self-Management: A Patient–Physician Perspective
This article is co-authored by five patients living with chronic obstructive pulmonary disease (COPD), and a primary care physician who has over 30 years of clinical experience and is involved in educating hea...
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Article
Open AccessIMP2ART: development of a multi-level programme theory integrating the COM-B model and the iPARIHS framework, to enhance implementation of supported self-management of asthma in primary care
Supported asthma self-management, incorporating an asthma action plan and annual clinical review, has been recommended by UK/global guidelines for over three decades. However, implementation remains poor, as o...
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Article
Open AccessA Charter to Fundamentally Change the Role of Oral Corticosteroids in the Management of Asthma
Asthma affects 339 million people worldwide, with an estimated 5–10% experiencing severe asthma. In emergency settings, oral corticosteroids (OCS) can be lifesaving, but acute and long-term treatment can produ...
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Article
Open AccessIMPlementing IMProved Asthma self-management as RouTine (IMP2ART) in primary care: study protocol for a cluster randomised controlled implementation trial
Asthma is a common long-term condition and major public health problem. Supported self-management for asthma that includes a written personalised asthma action plan, supported by regular professional review, r...
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Article
Open AccessA Renewed Charter: Key Principles to Improve Patient Care in Severe Asthma
Asthma is a heterogenous respiratory disease, usually associated with chronic airway inflammation and hyper-responsiveness, which affects an estimated 339 million people worldwide. Severe asthma affects approx...
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Article
Open AccessComparison of COPD primary care in England, Scotland, Wales, and Northern Ireland
Currently the National Asthma and COPD audit programme (NACAP) only undertakes audit of COPD primary care in Wales due to its near complete data coverage. We aimed to determine if the quality of COPD primary c...
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Article
Open AccessDevelo** a theoretically informed education programme within the context of a complex implementation strategy in UK primary care: an exemplar from the IMP2ART trial
IMPlementing IMProved Asthma self-management as RouTine (IMP2ART) is a programme of work develo** and evaluating a strategy for implementing supported asthma self-management in UK primary care. The strategy enc...
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Article
Open AccessGlobal Quality Standard for Identification and Management of Severe Asthma
Severe asthma is a debilitating, life-threatening disease associated with substantial global morbidity, mortality, and health care resource utilization. Patients may not receive guideline-directed medical care...
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Article
Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery
Mice engineered to express the entire human variable immunoglobulin region enable rapid isolation of high-affinity antibodies specific for antigens of interest.
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Article
Open AccessNovel study design to assess the utility of the copd assessment test in a primary care setting
The quality of a consultation provided by a physician can have a profound impact on the quality of care and patient engagement in treatment decisions. When the COPD Assessment Test (CAT) was developed, one of ...
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Article
Book reviews
Antibody Engineering — A Practical Approach.