13 Result(s)

Article

Greenhouse Gas Emissions from Respiratory Treatments: Results from the SABA CARBON International Study

Healthcare systems are looking to reduce their carbon impact. Short-acting β₂-agonist (SABA) overuse (≥ 3 canisters/year) is common in asthma and linked to poor outcomes; however, its environmental impact remains...

Ashraf Alzaabi, John P. Bell, Felicia Montero-Arias, David B. Price… in Advances in Therapy (2023)

Article

Author Correction: Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19

Urszula Radzikowska, Andrzej Eljaszewicz, Ge Tan, Nino Stocker… in Nature Communications (2023)

Article

Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19

Rhinoviruses and allergens, such as house dust mite are major agents responsible for asthma exacerbations. The influence of pre-existing airway inflammation on the infection with severe acute respiratory syndr...

Urszula Radzikowska, Andrzej Eljaszewicz, Ge Tan, Nino Stocker… in Nature Communications (2023)

Article

Application of an algorithm to analyze patterns of intermittent oral corticosteroid use in asthma

An algorithm to describe patterns of intermittent oral corticosteroid use in the UK (n = 476,167) found that one-third of patients receiving intermittent oral corticosteroids for asthma only had short gaps (<90 d...

John Haughney, Trung N. Tran, Heath Heatley… in npj Primary Care Respiratory Medicine (2023)

Article

A Renewed Charter: Key Principles to Improve Patient Care in Severe Asthma

Asthma is a heterogenous respiratory disease, usually associated with chronic airway inflammation and hyper-responsiveness, which affects an estimated 339 million people worldwide. Severe asthma affects approx...

Andrew Menzies-Gow, David J. Jackson, Mona Al-Ahmad… in Advances in Therapy (2022)

Article

Improving Care in Eosinophil-Associated Diseases: A Charter

Eosinophil-associated diseases (EADs) are a range of heterogeneous conditions in which eosinophils are believed to play a critical pathological role. EADs include common illnesses such as eosinophilic asthma a...

David J. Jackson, Praveen Akuthota, Rebeca Andradas… in Advances in Therapy (2022)

Article

International severe asthma registry (ISAR): protocol for a global registry

Severe asthma exerts a disproportionately heavy burden on patients and health care. Due to the heterogeneity of the severe asthma population, many patients need to be evaluated to understand the clinical featu...

J. Mark FitzGerald, Trung N. Tran, Marianna Alacqua… in BMC Medical Research Methodology (2020)

Article

Safety of Eosinophil-Depleting Therapy for Severe, Eosinophilic Asthma: Focus on Benralizumab

Eosinophils play a pivotal role in the inflammatory pathology of asthma and have been the target of new biologic treatments for patients with eosinophilic asthma. Given the central role of interleukin (IL)-5 i...

David J. Jackson, Stephanie Korn, Sameer K. Mathur, Peter Barker… in Drug Safety (2020)

Article

Ability of Serum IgE Concentration to Predict Exacerbation Risk and Benralizumab Efficacy for Patients with Severe Eosinophilic Asthma

For patients with eosinophilic asthma with allergic characteristics, understanding the key drivers of exacerbations is important to identify optimal treatment strategies. Benralizumab is an interleukin-5 recep...

David J. Jackson, Marc Humbert, Ian Hirsch, Paul Newbold… in Advances in Therapy (2020)

Article

Correction: Corrigendum: Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation

Nat. Med. 23, 681–691 (2017); published online 1 May 2017; corrected after print 12 July 2017 In the version of this article initially published, Dr. Nathan W Bartlett was inadvertently omitted from the author...

Marie Toussaint, David J Jackson, Dawid Swieboda, Anabel Guedán… in Nature Medicine (2017)