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Single-Incision and Natural Orifice Translumenal Endoscopic Surgery in Switzerland
Single-incision laparoscopy (SIL) and natural orifice translumenal endoscopic surgery (NOTES) aim at reducing surgical access trauma. To monitor the introduction of emerging technologies, the Swiss Association...
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Article
Operation time and body mass index are significant risk factors for surgical site infection in laparoscopic sigmoid resection: a multicenter study
Surgical site infection (SSI) in patients who underwent colorectal surgery is a common complication associated with increased morbidity and costs. The aim of this study was to assess risk factors for SSI in la...
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Article
Laparoscopic incisional hernia repair is feasible and safe after liver transplantation
Incisional hernia is a common complication after liver transplantation. The current study evaluated incidence and risk factors for incisional hernia and compared laparoscopic and open hernia repair in terms of...
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Article
Effective Treatment of Advanced Colorectal Cancer by Rapamycin and 5-FU/Oxaliplatin Monitored by TIMP-1
The mTOR-inhibitor rapamycin has shown antitumor activity in various tumors. Bedside observations have suggested that rapamycin may be effective as a treatment for colorectal carcinomatosis.
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Who Should Do NOTES? Initial Endoscopic Performance of Laparoscopic Surgeons Compared to Gastroenterologists and Untrained Individuals
Natural orifice transluminal endoscopic surgery (NOTES) is a multidisciplinary surgical technique. If conventional endoscopic instrumentation can be easily mastered, surgeons with laparoscopic experience could...
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Article
Diagnosis and Management of the Symptomatic Duodenal Diverticulum: a Case Series and a Short Review of the Literature
The incidence of duodenal diverticula (DD) found at autopsy may be as high as 22%. Perforation is the least frequent but also the most serious complication. This case series gives an overview of the management...
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Genetically Targeted Cancer Therapy
The is a double-stranded RNA-activated protein kinase (PKR) has been largely investigated for its key role in viral host defense. Although best characterized by its function in mediating the antiviral and anti...
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Article
Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis
The transcription factor E2F-1 induces cell cycle progression at the G1/S checkpoint, and deregulation of E2F-1 provokes apoptosis in a wide variety of malignant cells. To date only p14ARF and p73, a p53 homologu...