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Article
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains
Chromosomal organization, scaling from the 147-base pair (bp) nucleosome to megabase-ranging domains encompassing multiple transcriptional units, including heritability loci for psychiatric traits, remains lar...
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Article
Open AccessA chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons
Midbrain dopaminergic neurons (MDN) represent 0.0005% of the brain’s neuronal population and mediate cognition, food intake, and metabolism. MDN are also posited to underlay the neurobiological dysfunction of ...
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Article
Convergence of placenta biology and genetic risk for schizophrenia
Defining the environmental context in which genes enhance disease susceptibility can provide insight into the pathogenesis of complex disorders. We report that the intra-uterine environment modulates the assoc...
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Chapter and Conference Paper
In Vivo NMR Measures of NAA and the Neurobiology of Schizophrenia
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Article
Regional cerebral blood flow asymmetries in a group of 189 normal subjects at rest
Regional cerebral blood flow (rCBF) asymmetries were studied in 189 subjects (96 males and 93 females) at rest with the133Xenon inhalation method using a fixed detector system. rCBF asymmetries in the resting con...