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Article
Imaging of the intracranial venous system with a contrast-enhanced volumetric interpolated examination
A contrast-enhanced interpolated, three-dimensional (3D) gradient-echo MR sequence with asymmetric k-space sampling, which we refer to as volumetric interpolated brain examination (VIBE), was evaluated for it...
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Article
Management of a Sporadic Malignant Subfrontal Peripheral Nerve Sheath Tumor
Malignant subfrontal (olfactory) peripheral nerve sheath tumors (MPNSTs) are exceedingly rare. Although meningiomas are the most common subfrontal extra-axial lesions, it is important to recognize that MPNSTs,...
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Article
Limitations of diffusion-weighted imaging in distinguishing between a brain tumor and a central nervous system histoplasmoma
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Article
Diffusion-weighted MR imaging abnormalities in pediatric patients with surgically-treated intracranial mass lesions
Diffusion-weighted imaging (DWI) is a magnetic resonance imaging (MRI) technique that measures the degree of water diffusion in vivo. DWI abnormalities are frequently observed on immediate postoperative imaging f...
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Chapter
Magnetic Resonance Spectroscopy
Magnetic resonance imaging (MRI) is the current standard neuroimaging modality for patients with high-grade gliomas (HGG). A valuable addition to the morphologic information obtained from MRI is magnetic reson...
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Article
Evaluation of MR markers that predict survival in patients with newly diagnosed GBM prior to adjuvant therapy
Purpose Glioblastoma Multiforme (GBM) is the most common and lethal primary brain tumor in adults. The goal of this study was to test the predictive value of MR parameters in relation to the survival of patients ...
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Article
Relationship of pre-surgery metabolic and physiological MR imaging parameters to survival for patients with untreated GBM
Glioblastoma Multiforme (GBM) are heterogeneous lesions, both in terms of their appearance on anatomic images and their response to therapy. The goal of this study was to evaluate the prognostic value of param...
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Article
Open AccessIntegration of preoperative anatomic and metabolic physiologic imaging of newly diagnosed glioma
Purpose To integrate standard anatomic magnetic resonance imaging in conjunction with uniformly acquired physiologic imaging biomarkers of untreated glioma with different histological gra...
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Article
Neuroimaging in neuro-oncology
Neuroimaging of brain tumors has evolved from a strictly morphology-based discipline to one that encompasses function, physiology, and anatomy. This review outlines the current imaging standard for patients wi...
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Chapter
Modern Neuroimaging of Pediatric Brain Tumors
Neuroimaging has been an important tool in the diagnosis and surveillance of brain tumors for more than 30 years. Although magnetic resonance (MR) imaging remains the most important imaging tool for assessing ...
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Chapter
Imaging of Brain Neoplasm
■ Brain imaging is necessary for optimal localization, characterization, and management of pediatric brain cancer prior to surgery in patients with suspected or confirmed brain tumors (strong evidence).
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Chapter
8 Imaging of Brain Cancer
Brain imaging is necessary for optimal localization, characterization, and management of brain cancer prior to surgery in patients with suspected or confirmed brain tumors (strong evidence). Due to its superio...
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Article
Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center study
We have tested the predictive value of apparent diffusion coefficient (ADC) histogram analysis in stratifying progression-free survival (PFS) and overall survival (OS) in bevacizumab-treated patients with rec...
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Article
Ferumoxytol-Enhanced MRI to Image Inflammation Within Human Brain Arteriovenous Malformations: a Pilot Investigation
Inflammation cell infiltration and cytokine expression are seen in the vascular walls and intervening stroma of resected brain arteriovenous malformation (bAVM) specimens, even in unruptured and previously unt...
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Reference Work Entry In depth
Brain Cancer: Evidence-Based Neuroimaging
The term brain cancer, more commonly referred to as brain tumor, is used here to describe all primary and secondary neoplasms of the brain and its covering, including the leptomeninges, dura, skull, and scalp....
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Article
Apparent diffusion coefficient in glioblastoma with PNET-like components, a GBM variant
Glioblastoma (GBM) with primitive neuroectodermal tumor (PNET)-like (GBM-PNET) components is a rare variant of GBM. Recent studies describe PNET-like clinical behavior in these patients—with significantly incr...
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Article
Open AccessAdult-onset central nervous system hemophagocytic lymphohistiocytosis: a case report
Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome with both genetic and acquired causes characterized by elevated cytokine levels, hyperinflammation, and overactivation of lymphocytes and macroph...
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Article
Open AccessSerial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab
Interpretation of changes in the T1- and T2-weighted MR images from patients with newly diagnosed glioblastoma (GBM) treated with standard of care in conjunction with anti-angiogenic agents is complicated by p...
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Article
Quantitative multi-modal MR imaging as a non-invasive prognostic tool for patients with recurrent low-grade glioma
Low-grade gliomas can vary widely in disease course and therefore patient outcome. While current characterization relies on both histological and molecular analysis of tissue resected during surgery, there rem...
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Article
Early tumor growth between initial resection and radiotherapy of glioblastoma: incidence and impact on clinical outcomes
Early tumor growth, or increased contrast-enhancing tumor not related to evolving post-surgical injury, in the interval between surgical resection and initiation of radiotherapy has implications for treatment ...
