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Open AccessIntegration of preoperative anatomic and metabolic physiologic imaging of newly diagnosed glioma
Purpose To integrate standard anatomic magnetic resonance imaging in conjunction with uniformly acquired physiologic imaging biomarkers of untreated glioma with different histological gra...
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Article
Neuroimaging in neuro-oncology
Neuroimaging of brain tumors has evolved from a strictly morphology-based discipline to one that encompasses function, physiology, and anatomy. This review outlines the current imaging standard for patients wi...
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Article
Open AccessAdult-onset central nervous system hemophagocytic lymphohistiocytosis: a case report
Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome with both genetic and acquired causes characterized by elevated cytokine levels, hyperinflammation, and overactivation of lymphocytes and macroph...
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Open AccessSerial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab
Interpretation of changes in the T1- and T2-weighted MR images from patients with newly diagnosed glioblastoma (GBM) treated with standard of care in conjunction with anti-angiogenic agents is complicated by p...
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Open AccessA fully automated artificial intelligence method for non-invasive, imaging-based identification of genetic alterations in glioblastomas
Glioblastoma is the most common malignant brain parenchymal tumor yet remains challenging to treat. The current standard of care—resection and chemoradiation—is limited in part due to the genetic heterogeneity...
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Open AccessTopographic correlates of driver mutations and endogenous gene expression in pediatric diffuse midline gliomas and hemispheric high-grade gliomas
We evaluate the topographic distribution of diffuse midline gliomas and hemispheric high-grade gliomas in children with respect to their normal gene expression patterns and pathologic driver mutation patterns....
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Open AccessAuthor Correction: Topographic correlates of driver mutations and endogenous gene expression in pediatric diffuse midline gliomas and hemispheric high-grade gliomas
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Open AccessEWSR1-BEND2 fusion defines an epigenetically distinct subtype of astroblastoma
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Open AccessFederated learning enables big data for rare cancer boundary detection
Although machine learning (ML) has shown promise across disciplines, out-of-sample generalizability is concerning. This is currently addressed by sharing multi-site data, but such centralization is challenging...
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Open AccessAuthor Correction: Federated learning enables big data for rare cancer boundary detection