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Article
Open AccessImpaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis
Regulation of cutaneous immunity is severely compromised in inflammatory skin disease. To investigate the molecular crosstalk underpinning tolerance versus inflammation in atopic dermatitis, we utilise a human...
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Article
Open AccessGenomic programming of IRF4-expressing human Langerhans cells
Langerhans cells (LC) can prime tolerogenic as well as immunogenic responses in skin, but the genomic states and transcription factors (TF) regulating these context-specific responses are unclear. Bulk and sin...
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Article
Open Access6th International Symposium on Molecular Allergology (ISMA)
ORAL ABSTRACTS
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Article
Open AccessStructural studies of novel glycoconjugates from polymerized allergens (allergoids) and mannans as allergy vaccines
Immunotherapy for treating IgE-mediated allergies requires high doses of the corresponding allergen. This may result in undesired side effects and, to avoid them, hypoallergenic allergens (allergoids) polymeri...
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Article
Open AccessThe 11S globulin Sin a 2 from yellow mustard seeds shows IgE cross-reactivity with homologous counterparts from tree nuts and peanut
The 11S globulin Sin a 2 is a marker to predict severity of symptoms in mustard allergic patients. The potential implication of Sin a 2 in cross-reactivity with tree nuts and peanut has not been investigated s...
