11 Result(s)
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Siyu Wang
Internal Medicine
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Article
The prevalence of oral frailty among older adults: a systematic review and meta‑analysis
This study is the first to explore the prevalence of oral frailty among older adults through systematic review and meta‑analysis.
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Article
A novel immune checkpoint-related signature for prognosis and immune analysis in breast cancer
Breast cancer is one of the most prevailing forms of cancer globally. Immunotherapy has demonstrated efficacy in improving the overall survival of breast cancer. The aim of us was to formulate a novel signatur...
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Article
Open AccessType 2 diabetes mellitus plays a protective role against osteoporosis --mendelian randomization analysis
Type 2 diabetes mellitus (DM2) and osteoporosis (OP) are currently the two most significant causes of mortality and morbidity in older adults, according to clinical evidence. The intrinsic link between them is...
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Article
Open AccessShort-term PET-derived kinetic estimation for the diagnosis of hepatocellular carcinoma: a combination of the maximum-slope method and dual-input three-compartment model
Kinetic estimation provides fitted parameters related to blood flow perfusion and fluorine-18-fluorodeoxyglucose (18F-FDG) transport and intracellular metabolism to characterize hepatocellular carcinoma (HCC) but...
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Article
Development and external validation of a stability machine learning model to identify wake-up stroke onset time from MRI
To develop and externally validate a machine learning (ML) model based on diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) to identify the onset time of wake-up stroke from MRI.
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Article
Open AccessRisk factors that affect the degree of bronchopulmonary dysplasia in very preterm infants: a 5-year retrospective study
Bronchopulmonary dysplasia (BPD) is one of the most common adverse consequence of premature delivery and the most common chronic lung disease in infants. BPD is associated with long-term lung diseases and neur...
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Article
Open AccessHuman umbilical cord mesenchymal stem cell transfusion in immune non-responders with AIDS: a multicenter randomized controlled trial
We examined the safety and efficacy of human umbilical cord mesenchymal stem cell (hUC-MSC) infusion for immune non-responder (INR) patients with chronic HIV-1 infection, who represent an unmet medical need ev...
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Open AccessEffect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial
Treatment of severe Coronavirus Disease 2019 (COVID-19) is challenging. We performed a phase 2 trial to assess the efficacy and safety of human umbilical cord-mesenchymal stem cells (UC-MSCs) to treat severe C...
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Article
Hypothalamus-pituitary-adrenal Axis in Glucolipid metabolic disorders
With the change of life style, glucolipid metabolic disorders (GLMD) has become one of the major chronic disorders causing public health and clinical problems worldwide. Previous studies on GLMD pay more atten...
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Article
Open AccessHuman umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19: a phase 1 clinical trial
No effective drug treatments are available for coronavirus disease 2019 (COVID-19). Host-directed therapies targeting the underlying aberrant immune responses leading to pulmonary tissue damage, death, or long...
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Open AccessHow Serious is the Economic Burden of Diabetes Mellitus in Hainan Province? A Study Based on “System of Health Account 2011”
The treatment of diabetes requires extensive use of healthcare resources, resulting in high medical costs, which in turn places a heavy economic burden on society, patients and their families.
