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    Article

    Decline of lymphatic vessel density and function in murine skin during aging

    Lymphatic vessels play important roles in the pathogenesis of many conditions that have an increased prevalence in the elderly population. However, the effects of the aging process on the lymphatic system are ...

    Sinem Karaman, Dorina Buschle, Paola Luciani, Jean-Christophe Leroux in Angiogenesis (2015)

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    Open Access

    Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling

    Lymphatic vessels play important roles in fluid drainage and in immune responses, as well as in pathological processes including cancer progression and inflammation. While the molecular regulation of the earli...

    Alexandra M. Ochsenbein, Sinem Karaman, Steven T. Proulx, Rhea Goldmann in Angiogenesis (2016)

  3. Article

    Open Access

    Alternative transcription of a shorter, non-anti-angiogenic thrombospondin-2 variant in cancer-associated blood vessels

    Thrombospondin-2 (TSP2) is an anti-angiogenic matricellular protein that inhibits tumor growth and angiogenesis. Tumor-associated blood vascular endothelial cells (BECs) were isolated from human invasive bladd...

    Filip Roudnicky, Sun Young Yoon, Susanna Poghosyan, Simon Schwager in Oncogene (2018)