10 Result(s)
within
Siddappa N Byrareddy
Virology
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Article
Open AccessIdentification and Biological Characterization of Unique B/C Recombinant Strains of HIV-1 In Southern States of India
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Article
Open AccessPassive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose
A key goal for HIV-1 envelope immunogen design is the induction of cross-reactive neutralizing antibodies (nAbs). As AIDS vaccine recipients will not be exposed to strains exactly matching any immunogens due t...
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Article
Host-Virus Interaction of ZIKA Virus in Modulating Disease Pathogenesis
The Zika virus (ZIKV) is a newly emerging pathogen that has resulted in a worldwide epidemic. It primarily spreads either through infected Aedes aegypti or Aedes albopictus mosquitos leading to severe neurologica...
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Article
Functional Meningeal Lymphatics and Cerebrospinal Fluid Outflow
Functional meningeal lymphatic system plays a crucial role in outflow of cerebrospinal fluid. Metabolites and neurotoxins in the cerebrospinal fluid may be excreted via this system and accumulate in the cervic...
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Article
FDC:TFH Interactions within Cervical Lymph Nodes of SIV-Infected Rhesus Macaques
Cerebrospinal fluid (CSF) drains via the lymphatic drainage pathway. This lymphatic pathway connects the central nervous system (CNS) to the cervical lymph node (CLN). As the CSF drains to CLN via the dural an...
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Article
In vivo characterization of macrophage-tropic simian immunodeficiency virus molecular clones in rhesus macaques
Macrophages are a major target of HIV/SIV infection and play an important role in pathogenesis by serving as viral reservoirs in the central nervous system. Previously, a unique early SIVmac251 envelope (Env) ...
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Article
SARS-CoV-2 Infection Leads to Neurological Dysfunction
A number of neurological disease complications have been seen following infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While most person with COVID-19 respiratory disease demo...
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Article
Infectivity of SARS-CoV-2: there Is Something More than D614G?
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Article
Open AccessAn emerging and variant viral promoter of HIV-1 subtype C exhibits low-level gene expression noise
We observe the emergence of several promoter-variant viral strains in India during recent years. The variant viral promoters contain additional copies of transcription factor binding sites present in the viral...
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Article
Chronic Opioid Administration is Associated with Prevotella-dominated Dysbiosis in SIVmac251 Infected, cART-treated Macaques
People living with the human immunodeficiency virus (HIV) have an elevated risk of opioid misuse due to both prescriptions for HIV-associated chronic pain and because injection drug use remains a primary mode ...
