-
Article
Open AccessCom probe implemented STexS II greatly enhances specificity in SARS-CoV-2 variant detection
The initial introduction of utilizing double helix structural oligonucleotides known as SNP ty** with excellent specificity (STexS) in a standard PCR greatly improved the detection of single nucleotide polym...
-
Article
Open AccessInclusion of double helix structural oligonucleotide (STexS) results in an enhance of SNP specificity in PCR
Genetic mutations such as single nucleotide polymorphisms (SNP) are known as one of the most common forms which related to various genetic disorders and cancers. Among of the methods developed for efficient de...
-
Article
Mutational biosynthesis of tacrolimus analogues by fkbO deletion mutant of Streptomyces sp. KCTC 11604BP
Tacrolimus (FK506) is an important macrocyclic polyketide showing antifungal and immunosuppressive activities, as well as neuroregenerative properties. Tacrolimus biosynthetic machinery should incorporate the ...
-
Article
Open AccessThe role of acyl-coenzyme A carboxylase complex in lipstatin biosynthesis of Streptomyces toxytricini
Streptomyces toxytricini produces lipstatin, a specific inhibitor of pancreatic lipase, which is derived from two fatty acid moieties with eight and 14 carbon atoms. The pccB gene locus in 10.6 kb fragment of S. ...
-
Article
Allergenicity test of genetically modified soybean in Sprague Dawley rats
Allergenicity of genetically-modified (GM) soybean was evaluated in male Sprague Dawley rats. To confirm the CM soybean used in this study, the polymerase chain reaction (PCR) was performed using the chromosom...
