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    Article

    Tumour circular RNAs elicit anti-tumour immunity by encoding cryptic peptides

    Emerging data have shown that previously defined noncoding genomes might encode peptides that bind human leukocyte antigen (HLA) as cryptic antigens to stimulate adaptive immunity1,2. However, the significance an...

    Di Huang, **aofeng Zhu, Shuying Ye, Jiahui Zhang, Jianyou Liao, Ning Zhang in Nature (2024)

  2. Article

    Open Access

    Long noncoding RNA DIO3OS induces glycolytic-dominant metabolic reprogramming to promote aromatase inhibitor resistance in breast cancer

    Aromatase inhibition is an efficient endocrine therapy to block ectopic estrogen production for postmenopausal estrogen receptor (ER)-positive breast cancer patients, but many develop resistance. Here, we show...

    Xueman Chen, Rong Luo, Yunmei Zhang, Shuying Ye, **n Zeng in Nature Communications (2022)