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Article
Open AccessDermotoscope assisted diagnosis of adolescent bullous pilomatricoma: six case reports
Pilomatricoma (PM) is a cutaneous benign neoplasm derived from the hair matrix. It clinically presents as a solitary and firm nodule overlying normal epidermis and is usually not easy to be noticed at early st...
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Article
Liraglutide Improves PCOS Symptoms in Rats by Targeting FDX1
Polycystic ovary syndrome (PCOS) is a gynecological endocrine disorder characterized by ovulatory disorders, hyperandrogenemia, and polycystic changes in the ovaries. FDX1 is a ferredoxin-reducing protein on h...
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Article
Robust Fisher-regularized extreme learning machine with asymmetric Welsch-induced loss function for classification
In general, it is a worth challenging problem to build a robust classifier for data sets with noises or outliers. Establishing a robust classifier is a more difficult problem for datasets with asymmetric noise...
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Article
Deciphering Autoimmune Diseases: Unveiling the Diagnostic, Therapeutic, and Prognostic Potential of Immune Repertoire Sequencing
Autoimmune diseases (AIDs) are immune system disorders where the body exhibits an immune response to its own antigens, causing damage to its own tissues and organs. The pathogenesis of AIDs is incompletely und...
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Article
Parallel degradome-seq and DMS-MaPseq substantially revise the miRNA biogenesis atlas in Arabidopsis
MicroRNAs (miRNAs) are produced from highly structured primary transcripts (pri-miRNAs) and regulate numerous biological processes in eukaryotes. Due to the extreme heterogeneity of these structures, the initi...
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Article
Open AccessMT1G induces lipid droplet accumulation through modulation of H3K14 trimethylation accelerating clear cell renal cell carcinoma progression
Lipid droplet formation is a prominent histological feature in clear cell renal cell carcinoma (ccRCC), but the significance and mechanisms underlying lipid droplet accumulation remain unclear.
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Article
Characterization of Holomorphic Invariant Complex Finsler Metrics and Schwarz Lemma on the Polyball
A domain \(\pmb {B}\subset \mathbb {C}^N\) B ...
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Article
Graphene membranes with pyridinic nitrogen at pore edges for high-performance CO2 capture
Membranes based on a porous two-dimensional selective layer offer the potential to achieve exceptional performance to improve energy efficiency and reduce the cost for carbon capture. So far, separation from t...
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Article
High-density map** of durable and broad-spectrum stripe rust resistance gene Yr30 in wheat
The durable stripe rust resistance gene Yr30 was fine-mapped to a 610-kb region in which five candidate genes were identified by expression analysis and sequence polymorphisms.
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Article
Open AccessBoosting the sonodynamic performance of CoBiMn-layered double hydroxide nanoparticles via tumor microenvironment regulation for ultrasound imaging-guided sonodynamic therapy
Sonodynamic therapy (SDT), a promising strategy for cancer treatment with the ability for deep tissue penetration, has received widespread attention in recent years. Sonosensitizers with intrinsic characterist...
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Article
Potential use of maize–peanut intercrop** to adapt to drought and nitrogen–shortage impacts
The objective of this study was to propose a maize–peanut intercrop** system for traditional sole maize to increase economic benefits and decrease environmental pollution for dryland farming.
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Article
Open AccessPopulation genomics and epigenomics of Spirodela polyrhiza provide insights into the evolution of facultative asexuality
Many plants are facultatively asexual, balancing short-term benefits with long-term costs of asexuality. During range expansion, natural selection likely influences the genetic controls of asexuality in these ...
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Article
Open AccessElectrochemical-repaired porous graphene membranes for precise ion-ion separation
The preparation of atom-thick porous lattice hosting Å-scale pores is attractive to achieve a large ion-ion selectivity in combination with a large ion flux. Graphene film is an ideal selective layer for this ...
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Article
Open AccessTernary heterostructure-driven photoinduced electron-hole separation enhanced oxidative stress for triple-negative breast cancer therapy
Zinc oxide nanoparticles (ZnO NPs) stand as among the most significant metal oxide nanoparticles in trigger the formation of reactive oxygen species (ROS) and induce apoptosis. Nevertheless, the utilization of...
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Article
Open AccessPolymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21
Single nuclear polymorphisms (SNPs) have been published to be correlated with multiple diseases. Transcription Factor 21 (TCF21) is a critical transcription factor involved in various types of cancers. However...
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Article
Spiking SiamFC++: deep spiking neural network for object tracking
Spiking neural network (SNN) is a biologically-plausible model and exhibits advantages of high computational capability and low power consumption. While the training of deep SNN is still an open problem, which...
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Article
Complex dynamics of an SIRS epidemic model with non-monotone incidence and saturated cure rate
The study of infectious disease models plays an important theoretical role in the prevention and control of diseases. In this paper, according to the influence of psychological effect and the maximum therapeut...
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Article
Effect of ECAP on Mechanical Properties and Corrosion Resistance of 2024-CNTs@Ni Composite
The 2024-1.5 wt%CNTs@Ni (Nickel-coated carbon nanotubes) composite were subjected to equal channel angle pressing (ECAP) deformation treatment and the microstructure, hardness distribution and tensile properti...
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Article
Microneedle assisted delivery of epidermal and dermal stem cells to promote hair growth
Advances in effective treatment options for hair loss hold paramount importance for individuals on both psychological and physical levels. Cell-based therapies for hair loss hold great promise due to their pot...
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Article
Open AccessAnterior chamber proliferative membrane interception (AC-PMI)-enhanced trabeculectomy versus trabeculectomy for treating neovascular glaucoma: protocol for a randomized controlled trial
Neovascular glaucoma (NVG) is an irreversible blinding eye disease worldwide and is classified as one of the refractory glaucoma conditions, severely impacting visual function and vision. Unfortunately, effect...
