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Article
The m6A methyltransferase METTL3 drives neuroinflammation and neurotoxicity through stabilizing BATF mRNA in microglia
Persistent neuroinflammation and progressive neuronal loss are defining features of acute brain injury including traumatic brain injury (TBI) and cerebral stroke. Microglia, the most abundant type of brain-res...
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Article
Endoscopic endonasal resection of symptomatic Rathke’s cleft cysts: outcomes of the strategy to maintain the fenestration open
Purpose: The study intends to clarify the optimal endoscopic endonasal surgical strategy for symptomatic Rathke’s cleft cysts (RCCs). Methods: We retrospectively analyzed patients with RCCs that underwent EEA ...
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Article
Course and predictors of supportive care needs among colorectal cancer survivors with ostomies: a longitudinal study
Although there is a growing emphasis on supportive care for cancer patients, those with colorectal cancer (CRC) who have ostomies require special attention in terms of their physical, psychological, spiritual,...
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Article
Open AccessFNDC5 prevents oxidative stress and neuronal apoptosis after traumatic brain injury through SIRT3-dependent regulation of mitochondrial quality control
Mitochondrial dysfunction and oxidative stress are important mechanisms for secondary injury after traumatic brain injury (TBI), which result in progressive pathophysiological exacerbation. Although the Fibron...
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Article
Open AccessHIF-2α/LINC02609/APOL1-mediated lipid storage promotes endoplasmic reticulum homeostasis and regulates tumor progression in clear-cell renal cell carcinoma
The VHL-HIF pathway and lipid droplet accumulation are the main characteristics of clear cell renal cell carcinoma (ccRCC). However, the connection between the two features is largely unknown.
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Article
Open AccessColoration differences in three Camellia reticulata Lindl. cultivars: ‘Tongzimian’, ‘Shizitou’ and ‘Damanao’
Camellia reticulata Lindl., also known as Yunnan Camellia, is an important ornamental plant in China, especially for its large and stunning flowers. A comprehensive understanding of their coloration mechanisms ca...
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Chapter and Conference Paper
Architecture Simulation of Unmanned Lunar Exploration Platform Based on Modelica
Faced to the multi-system collaboration of lunar exploration platform, the multi-level and multi-domain simulation model is built, based on the Modelica simulation language. The simulation model realizes the m...
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Article
Correction to: Recombinant Adiponectin Peptide Ameliorates Brain Injury Following Intracerebral Hemorrhage by Suppressing Astrocyte-Derived Inflammation via the Inhibition of Drp1-Mediated Mitochondrial Fission
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Article
An alternative extension of telomeres related prognostic model to predict survival in lower grade glioma
The alternative extension of the telomeres (ALT) mechanism is activated in lower grade glioma (LGG), but the role of the ALT mechanism has not been well discussed. The primary purpose was to demonstrate the si...
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Article
Open AccessConstruction and validation of a risk assessment model for acute kidney injury in patients with acute pancreatitis in the intensive care unit
To construct and validate a risk assessment model for acute kidney injury (AKI) in patients with acute pancreatitis (AP) in the intensive care unit (ICU).
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Article
Open AccessComparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis
Metastases within liver or the brain are the most common causes of mortality from lung cancer (LC). Predicting liver or brain metastases before having evidence from imaging of the tumors is challenging but imp...
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Article
The incidence and risk factors of unplanned reoperation in endoscopic endonasal surgeries: a single center study
The incidence of unplanned reoperation after surgery during the same hospitalization is considered one of most important evaluation indicators for health care quality. The purpose of this study was to determin...
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Article
Publisher Correction to: Clinical outcomes and safety of large or giant vestibular schwannoma in older patients undergoing microsurgery: a matched cohort study
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Article
Clinical outcomes and safety of large or giant vestibular schwannoma in older patients undergoing microsurgery: a matched cohort study
To compare the clinical outcomes of large or giant vestibular schwannomas (VSs) between older patients and younger patients who underwent microsurgery and to explore whether the incidence of postoperative comp...
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Article
Open AccessChinese expert consensus on the management of aneurysmal subarachnoid hemorrhage-related hydrocephalus
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Article
Open AccessSLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma
Glioma is the most common type of primary malignant tumor in the central nervous system with limited treatment satisfaction. Finding new therapeutic targets has remained a major challenge. Ferroptosis is a nov...
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Article
Open AccessThe effect of postoperative early lumbar drainage on delayed fever after cerebellopontine angle tumour surgery: study protocol for a randomized controlled trial
Postoperative fever is one of the common complications in neurosurgery, and intracranial aseptic inflammation and infection are important risk factors. Continuous drainage of cerebrospinal fluid (CSF) via lumb...
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Article
Estrogen Up-Regulates Iron Transporters and Iron Storage Protein Through Hypoxia Inducible Factor 1 Alpha Activation Mediated by Estrogen Receptor β and G Protein Estrogen Receptor in BV2 Microglia Cells
Estrogen is a steroid hormone produced mainly by the ovaries. It has been found that estrogen could regulate iron metabolism in neurons and astrocytes in different ways. The role of estrogen on iron metabolism...
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Article
Open AccessLRRC15+ myofibroblasts dictate the stromal setpoint to suppress tumour immunity
Recent single-cell studies of cancer in both mice and humans have identified the emergence of a myofibroblast population specifically marked by the highly restricted leucine-rich-repeat-containing protein 15 (...
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Article
Densely granulated adenoma pattern is associated with an increased risk of obstructive sleep apnea in patients with acromegaly
To explore the prevalence of obstructive sleep apnea (OSA) and the association between the adenoma granulation patterns and OSA in patients with acromegaly.
