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    Article

    Zinc deficiency induces hypertension by paradoxically amplifying salt sensitivity under high salt intake in mice

    Hypertension is one of the major etiologies that cause chronic kidney disease (CKD) and can exacerbate kidney dysfunction. Zinc is an essential trace element playing a role in blood pressure regulation, and zi...

    Marie Yamamoto, Tomoaki Takata, Hinako Hanada in Clinical and Experimental Nephrology (2024)

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    Open Access

    Renal tubular acidosis without interstitial nephritis in Sjögren’s syndrome: a case report and review of the literature

    Renal tubular acidosis is the principal clinical feature associated with tubulointerstitial nephritis in patients with primary Sjögren’s syndrome. Renal tubular dysfunction due to interstitial nephritis has be...

    Shintaro Hamada, Tomoaki Takata, Kentaro Yamada, Marie Yamamoto in BMC Nephrology (2023)

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    Article

    Creatinine generation rate can detect sarcopenia in patients with hemodialysis

    Sarcopenia is strongly associated with long-term mortality in patients undergoing hemodialysis. The diagnostic modalities used to assess muscle mass, such as bioimpedance analysis and dual-energy X-ray absorpt...

    Yukari Mae, Tomoaki Takata, Kentaro Yamada in Clinical and Experimental Nephrology (2022)

  4. Article

    Open Access

    Skeletal muscle mass is associated with erythropoietin response in hemodialysis patients

    Hyporesponsiveness to erythropoietin stimulating agent (ESA) is associated with poor outcomes in patients with chronic kidney disease. Although ESA hyporesponsiveness and sarcopenia have a common pathophysiolo...

    Tomoaki Takata, Yukari Mae, Kentaro Yamada, Sosuke Taniguchi in BMC Nephrology (2021)

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    Article

    Feasibility of computed tomography-based assessment of skeletal muscle mass in hemodialysis patients

    Sarcopenia is a major health issue especially in patients on maintenance hemodialysis. Low skeletal muscle mass is included in the diagnostic criteria for sarcopenia. The skeletal muscle mass is usually evalua...

    Tomoaki Takata, Aki Motoe, Katsumi Tanida, Sosuke Taniguchi in Journal of Nephrology (2021)

  6. Article

    Open Access

    Peritoneal dialysis-associated peritonitis caused by Mycobacteroides massiliense: the first case and review of the literature

    Peritoneal dialysis (PD)-associated peritonitis caused by nontuberculous Mycobacterium is rare; however, the number of cases has increased over the past decades. Mycobacteroides massiliense is a subspecies of the...

    Shintaro Hamada, Tomoaki Takata, Tsuyoshi Kitaura, Chiori Teraoka in BMC Nephrology (2021)

  7. Article

    Open Access

    A novel method for assessing the renal biopsy specimens using an activatable fluorescent probe

    Gamma-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG) is an activatable fluorescent probe that can be activated by γ-glutamyltranspeptidase (GGT). The expression of GGT in the kidney, which is one of the ma...

    Takuji Iyama, Tomoaki Takata, Kentaro Yamada, Yukari Mae in Scientific Reports (2020)