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Article
Zinc deficiency induces hypertension by paradoxically amplifying salt sensitivity under high salt intake in mice
Hypertension is one of the major etiologies that cause chronic kidney disease (CKD) and can exacerbate kidney dysfunction. Zinc is an essential trace element playing a role in blood pressure regulation, and zi...
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Article
Open AccessRenal tubular acidosis without interstitial nephritis in Sjögren’s syndrome: a case report and review of the literature
Renal tubular acidosis is the principal clinical feature associated with tubulointerstitial nephritis in patients with primary Sjögren’s syndrome. Renal tubular dysfunction due to interstitial nephritis has be...
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Article
Creatinine generation rate can detect sarcopenia in patients with hemodialysis
Sarcopenia is strongly associated with long-term mortality in patients undergoing hemodialysis. The diagnostic modalities used to assess muscle mass, such as bioimpedance analysis and dual-energy X-ray absorpt...
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Article
Open AccessSkeletal muscle mass is associated with erythropoietin response in hemodialysis patients
Hyporesponsiveness to erythropoietin stimulating agent (ESA) is associated with poor outcomes in patients with chronic kidney disease. Although ESA hyporesponsiveness and sarcopenia have a common pathophysiolo...
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Article
Feasibility of computed tomography-based assessment of skeletal muscle mass in hemodialysis patients
Sarcopenia is a major health issue especially in patients on maintenance hemodialysis. Low skeletal muscle mass is included in the diagnostic criteria for sarcopenia. The skeletal muscle mass is usually evalua...
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Article
Open AccessA novel method for assessing the renal biopsy specimens using an activatable fluorescent probe
Gamma-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG) is an activatable fluorescent probe that can be activated by γ-glutamyltranspeptidase (GGT). The expression of GGT in the kidney, which is one of the ma...