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Article
Open AccessComparing deep learning and handcrafted radiomics to predict chemoradiotherapy response for locally advanced cervical cancer using pretreatment MRI
Concurrent chemoradiotherapy (CRT) is the standard treatment for locally advanced cervical cancer (LACC), but its responsiveness varies among patients. A reliable tool for predicting CRT responses is necessary...
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Article
Improvement of Oxidative Stress-induced Cytotoxicity of Angelica keiskei (Miq.) Koidz. Leaves Extract through Activation of Heme Oxygenase-1 in C2C12 Murine Myoblasts
Angelica keiskei, (Miq.) Koidz. has been traditionally used as a food and medicinal resource in Asia including Korea. Although extracts or components of this plant are known to possess various pharmacological act...
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Article
Activation of Heme Oxygenase-1 is Involved in the Preventive Effect of Honokiol against Oxidative Damage in Human Retinal Pigment Epithelial Cells
Previous studies have shown that honokiol, a bioactive compound originated from the Magnolia, has beneficial effects on various chronic diseases. Although our previous study has demonstrated that honokiol effecti...
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Article
Validation of a nomogram for predicting the risk of lymphedema following contemporary treatment for breast cancer: a large multi-institutional study (KROG 20-05)
We previously constructed a nomogram for predicting the risk of arm lymphedema following contemporary breast cancer treatment. This nomogram should be validated in patients with different background characteri...
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Article
Influence of Irradiation on Capsules of Silicone Implants Covered with Acellular Dermal Matrix in Mice
In advanced breast cancer, radiotherapy is recommended as adjuvant therapy following breast reconstructive surgery. This inevitably led to growing concerns over possible complications of radiotherapy on implan...
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Article
Open AccessMap** patterns of para-aortic lymph node recurrence in cervical cancer: a retrospective cohort analysis
To map anatomic patterns of para-aortic lymph node (PALN) recurrence in cervical cancer patients and validate currently available guidelines on PA clinical target volumes (CTV).
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Article
Initial experience of preoperative short-course radiotherapy followed by oxaliplatin-based consolidation chemotherapy for locally advanced rectal cancer
We analyzed the safety and feasibility of preoperative short-course radiotherapy (SCRT) followed by consolidation chemotherapy for patients with locally advanced rectal cancer (LARC).
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Article
Open AccessRobustness of magnetic resonance radiomic features to pixel size resampling and interpolation in patients with cervical cancer
Radiomics is a promising field in oncology imaging. However, the implementation of radiomics clinically has been limited because its robustness remains unclear. Previous CT and PET studies suggested that radio...
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Article
Indole-6-carboxaldehyde prevents oxidative stress-induced mitochondrial dysfunction, DNA damage and apoptosis in C2C12 skeletal myoblasts by regulating the ROS-AMPK signaling pathway
Indole-6-carboxaldehyde (I6CA), a natural indole derivative derived from the brown algae Sargassum thunbergii (Mertens) Kuntze, is known to have several pharmacological activities. However, the antioxidant effect...
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Article
Open AccessMagnetic resonance imaging features of tumor and lymph node to predict clinical outcome in node-positive cervical cancer: a retrospective analysis
Current chemoradiation regimens for locally advanced cervical cancer are fairly uniform despite a profound diversity of treatment response and recurrence patterns. The wide range of treatment responses and pro...
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Article
Continuous risk profile and clustering-based method for investigating the effect of the automated enforcement system on urban traffic collisions
The automated enforcement systems (AESs), which detect speeding vehicles or vehicles that violate traffic signals, are installed and operated on urban arterial roadways to prevent traffic collisions and reduce...
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Article
Open AccessEnhancing prognosis prediction using pre-treatment nodal SUVmax and HPV status in cervical squamous cell carcinoma
This study was to evaluate the prognostic value of metabolic parameters on F-18-FDG PET/CT and the status of human papillomavirus (HPV) infection and known prognostic variables for predicting tumor recurrence ...
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Chapter and Conference Paper
K-Means and CRP-Based Characteristic Investigating Method of Traffic Accidents with Automated Speed Enforcement Cameras
Traffic speed enforcement cameras are used to reduce speeding, which is a major element in increasing the frequency and severity from traffic accidents in urban areas. Existing researches have focused on the a...
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Article
Open AccessInduction of apoptosis by Moutan Cortex Radicis in human gastric cancer cells through the activation of caspases and the AMPK signaling pathway
Moutan Cortex Radicis, the root bark of Paeonia × suffruticosa Andrews, Paeoniaceae, has been widely used in traditional medicine therapy. Although it has been shown to possess many pharmacological activities, th...
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Article
Alternative fiducial markers for Vero real-time tumor tracking radiotherapy: A phantom study
The objective of this study was to investigate the feasibility of potential fiducial markers consisting of various materials in a Vero real-time tumor-tracking (RTTT) system. In order to determine the applicab...
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Article
Open AccessTargeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer
Therapeutic interventions in the insulin-like growth factor receptor (IGF-1R) pathway were expected to provide clinical benefits; however, IGF-1R tyrosine kinase inhibitors (TKIs) have shown limited antitumor ...
