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Article
Influence of Nozzle Temperature on Gas Emissions and Mechanical Properties in Material Extrusion-based Additive Manufacturing of Super Engineering Plastics
Gas emissions pose significant environmental and health concerns in thermal processes involving thermoplastic polymers. This issue also extends to material extrusion (MEX) additive manufacturing (AM), which is...
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Article
The risk of preterm birth in women with history of short cervix delivering at term in the previous pregnancy: a retrospective cohort study
To investigate whether women with a short cervical length (CL), but delivered at term in the first pregnancy might have increased risks of having short cervix and spontaneous preterm birth (sPTB) in the subseq...
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Article
Open AccessPrimary ovarian high-grade endometrial stromal sarcoma: a case report
Primary ovarian high-grade endometrial stromal sarcoma is a very rare disease. Even though it has poor prognosis, the gold standard treatment has not been established owing to its rarity. This report aimed to ...
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Article
Open AccessRational design of a robust aluminum metal-organic framework for multi-purpose water-sorption-driven heat allocations
Adsorption-driven heat transfer technology using water as working fluid is a promising eco-friendly strategy to address the exponential increase of global energy demands for cooling and heating purposes. Here ...
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Article
Open AccessThe identification of candidate effective combination regimens for pancreatic cancer using the histoculture drug response assay
The prognosis for patients with pancreatic cancer is extremely poor, as they are resistant to first line chemotherapy. The long-term goal of this study was to identify effective combination chemotherapy for pa...
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Article
Open AccessFlexible loop and helix 2 domains of TCTP are the functional domains of dimerized TCTP
Translationally controlled tumor protein (TCTP), also called histamine releasing factor, is an evolutionarily conserved multifunctional protein in eukaryotes. We previously reported that extracellular TCTP acq...
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Article
A robust large-pore zirconium carboxylate metal–organic framework for energy-efficient water-sorption-driven refrigeration
The discovery of more-efficient and stable water adsorbents for adsorption-driven chillers for cooling applications remains a challenge due to the low working capacity of water sorption, high regeneration temp...
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Article
Open AccessDevelopment of a novel Hsp90 inhibitor NCT-50 as a potential anticancer agent for the treatment of non-small cell lung cancer
Despite the development of advanced therapeutic regimens such as molecular targeted therapy and immunotherapy, the 5-year survival of patients with lung cancer is still less than 20%, suggesting the need to de...
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Article
Open AccessSmall molecule activator of Nm23/NDPK as an inhibitor of metastasis
Nm23-H1/NDPK-A is a tumor metastasis suppressor having NDP kinase (NDPK) activity. Nm23-H1 is positively associated with prolonged disease-free survival and good prognosis of cancer patients. Approaches to inc...
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Article
Soluble epoxide hydrolase inhibitory activity of phenolic glycosides from Polygala tenuifolia and in silico approach
The goal of this study was to identify soluble epoxide hydrolase (sEH) inhibitors from plants. Our efforts led to the isolation of nine phenolic glycosides 1–9 from the roots of Polygala tenuifolia Willd. The str...
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Article
Open AccessA novel function of cIAP1 as a mediator of CHIP-driven eIF4E regulation
eIF4E is an initiator protein in cap-dependent translation. Its overexpression is linked to tumorigenesis in various human cancers, suggesting that the levels of eIF4E must be under tight control in normal cel...
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Article
Open AccessDevelopment of the Korean framework for senior-friendly hospitals: a Delphi study
Aging is an inevitable part of life. One can maintain well-being and wellness even after discharge and/or transition if his or her functional decline is minimized, sudden decline is prevented, and functioning ...
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Article
Selective nitrogen capture by porous hybrid materials containing accessible transition metal ion sites
Mesoporous metal–organic frameworks containing unsaturated Cr(III) sites are able to thermodynamically and selectively capture nitrogen from mixtures with oxygen and methane.
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Article
Development of accumulated heat stress index based on time-weighted function
Heat stress accumulates in the human body when a person is exposed to a thermal condition for a long time. Considering this fact, we have defined the accumulated heat stress (AH) and have developed the accumul...
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Article
Open AccessSTAT3-mediated IGF-2 secretion in the tumour microenvironment elicits innate resistance to anti-IGF-1R antibody
Drug resistance is a major impediment in medical oncology. Recent studies have emphasized the importance of the tumour microenvironment (TME) to innate resistance, to molecularly targeted therapies. In this st...
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Article
Open AccessTargeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer
Therapeutic interventions in the insulin-like growth factor receptor (IGF-1R) pathway were expected to provide clinical benefits; however, IGF-1R tyrosine kinase inhibitors (TKIs) have shown limited antitumor ...
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Article
Open AccessPhenotypic, immunologic, and clinical characteristics of patients with nontuberculous mycobacterial lung disease in Korea
This study aimed to elucidate the phenotypic, immunologic, and clinical characteristics of Korean patients with nontuberculous mycobacterial (NTM) lung disease and compare them with non-NTM bronchiectasis (BE)...
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Article
Open AccessActive pulmonary tuberculosis and latent tuberculosis infection among homeless people in Seoul, South Korea: a cross-sectional study
The aim of this study was to determine the prevalence rate of latent TB infection (LTBI) and active TB among homeless in Seoul metropolitan city, South Korea, and to compare the TB burden among homeless people...
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Article
Oligomerization of isobutene over aluminum chloride-loaded USY zeolite catalysts
Oligomerization of isobutene has been investigated over AlCl3-loaded USY zeolite catalysts in order to produce triisobutenes or remove/separate isobutene from C4 streams. Stable isobutene conversion and high sele...
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Article
Open AccessA highly annotated whole-genome sequence of a Korean individual
The genome of an anonymous Korean male has been sequenced using a broad spread of genomic techniques. This combinatorial approach allows for detailed characterization of sequence and structural variation. The ...
