-
Article
Open AccessMeta-analysis: loop ileostomy versus colostomy to prevent complications of anterior resection for rectal cancer
Anastomotic leakage is a serious complication of colorectal cancer surgery, prolonging hospital stays and impacting patient prognosis. Preventive colostomy is required in patients at risk of anastomotic fistul...
-
Article
Cutting all carbon–fluorine bonds from PFAS
Complete defluorination of per- and polyfluoroalkyl substances (PFAS) by a non-thermal technology is not easy to achieve. A rationally designed photochemical–electrochemical treatment train realizes complete d...
-
Article
Open AccessFerroptosis in early brain injury after subarachnoid hemorrhage: review of literature
Spontaneous subarachnoid hemorrhage (SAH), mainly caused by ruptured intracranial aneurysms, is a serious acute cerebrovascular disease. Early brain injury (EBI) is all brain injury occurring within 72 h after...
-
Article
ASO Author Reflections: Can Anesthesia Techniques Affect Neutrophil Extracellular Trap** Expression in Patients during Colorectal Cancer Surgery?
-
Article
Effect of Thoracic Epidural Anesthesia on Perioperative Neutrophil Extracellular Trap** Markers in Patients Undergoing Anesthesia and Surgery for Colorectal Cancer: A Randomized, Controlled Trial
Neutrophil extracellular trap** (NETosis) is an immunologic mechanism strongly linked with increased metastatic risk in colorectal cancer. The authors hypothesized that patients who received propofol–epidura...
-
Article
Road slope monitoring and early warning system integrating numerical simulation and image recognition: a case study of Nan**, Fujian, China
A novel road slope monitoring and early warning system was developed by integrating 3D image recognition technology and 3D numerical modeling technology for monitoring and predicting slope deformation. It was ...
-
Article
Open AccessAssociation of mitochondrial DNA variation with high myopia in a Han Chinese population
High myopia (HM), which is characterized by oxidative stress, is one of the leading causes of visual impairment and blindness across the world. Family and population genetic studies have uncovered nuclear-geno...
-
Article
Open AccessSustained productivity and agronomic potential of perennial rice
There is an urgent need for agricultural systems to intensify sustainably, increasing crop productivity, farmer livelihoods and soil health while using fewer resources. Crop perennialization, the conversion of...
-
Protocol
Generation of GM130 Conditional Knockout Mouse
The Golgi apparatus is a common and highly dynamic organelle in eukaryotic cells. It plays an important role in secretory trafficking and cargo modifications. Increasing evidence suggests that structural chang...
-
Article
GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells
Pulmonary surfactant is a lipid-protein complex secreted by alveolar type II epithelial cells and is essential for the maintenance of the delicate structure of mammalian alveoli to promote efficient gas exchan...
-
Article
Open AccessThe Elite Alleles of OsSPL4 Regulate Grain Size and Increase Grain Yield in Rice
Grain weight and grain number, the two important yield traits, are mainly determined by grain size and panicle architecture in rice. Herein, we report the identification and functional analysis of OsSPL4 in panic...
-
Article
Open AccessPRMT7 targets of Foxm1 controls alveolar myofibroblast proliferation and differentiation during alveologenesis
Although aberrant alveolar myofibroblasts (AMYFs) proliferation and differentiation are often associated with abnormal lung development and diseases, such as bronchopulmonary dysplasia (BPD), chronic obstructi...
-
Article
A multi-omics investigation of the composition and function of extracellular vesicles along the temporal trajectory of COVID-19
Exosomes represent a subtype of extracellular vesicle that is released through retrograde transport and fusion of multivesicular bodies with the plasma membrane1. Although no perfect methodologies currently exist...
-
Article
Open AccessGenetic relatedness among Ethiopian Oryza longistaminata populations and other AA genome Oryza species
Oryza longistaminata is the only AA-genome Oryza species that is perennial via rhizome production. This undomesticated rice species, which is native to Africa, is hypothesized to be a good candidate for expanding...
-
Article
Open AccessNeo-functionalization of a Teosinte branched 1 homologue mediates adaptations of upland rice
The rice orthologue of maize domestication gene Teosinte branched 1 (Tb1) affects tillering. But, unlike maize Tb1 gene, it was not selected during domestication. Here, we report that an OsTb1 duplicate gene (OsT...
-
Article
Resequencing of 683 common bean genotypes identifies yield component trait associations across a north–south cline
We conducted a large-scale genome-wide association study evaluation of 683 common bean accessions, including landraces and breeding lines, grown over 3 years and in four environments across China, ranging in l...
-
Article
Open AccessGasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis
Gasdermin D (GsdmD) was recently identified as the executioner of pyroptotic inflammatory cell death, and is a substrate for caspases-1 and 11. GsdmD is detrimental in lethal endotoxemia but protective in bact...
-
Article
Open AccessDecrease of gene expression diversity during domestication of animals and plants
The genetic mechanisms underlying the domestication of animals and plants have been of great interest to biologists since Darwin. To date, little is known about the global pattern of gene expression changes du...
-
Article
De novo assembly of a Chinese soybean genome
Soybean was domesticated in China and has become one of the most important oilseed crops. Due to bottlenecks in their introduction and dissemination, soybeans from different geographic areas exhibit extensive ...
-
Article
Coexpression network revealing the plasticity and robustness of population transcriptome during the initial stage of domesticating energy crop Miscanthus lutarioriparius
Coexpression network revealing genes with Co-variation Expression pattern (CE) and those with Top rank of Expression fold change (TE) played different roles in responding to new environment of Miscanthus lutarior...
