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Article
Mechanistic Investigation of Calcium Channel Regulation-Associated Genes in Pulmonary Arterial Hypertension and Signatures for Diagnosis
Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary disorder with complex causes. Calcium channel blockers have long been used in its treatment. Our study aimed to validate experimental results s...
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Article
Genome-wide association study reveals loci and candidate genes of flowering time in jute (Corchorus L.)
Suitable flowering time can improve fiber yield and quality, which is of great significance for jute biological breeding. In this study, 242 jute accessions were planted in Fujian for 2 consecutive years, and ...
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Article
Open AccessSingle-cell sequencing reveals the reproductive variations between primiparous and multiparous Hu ewes
In the modern sheep production systems, the reproductive performance of ewes determines the economic profitability of farming. Revealing the genetic mechanisms underlying differences in the litter size is impo...
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Article
Open AccessGait asymmetry in children with Duchenne muscular dystrophy: evaluated through kinematic synergies and muscle synergies of lower limbs
Gait is a complex, whole-body movement that requires the coordinated action of multiple joints and muscles of our musculoskeletal system. In the context of Duchenne muscular dystrophy (DMD), a disease characte...
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Article
Open AccessAge-related differences in gait symmetry obtained from kinematic synergies and muscle synergies of lower limbs during childhood
The age-related changes of gait symmetry in healthy children concerning individual joint and muscle activation data have previously been widely studied. Extending beyond individual joints or muscles, identifyi...
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Article
Open AccessEthanol yield improvement in Saccharomyces cerevisiae GPD2 Delta FPS1 Delta ADH2 Delta DLD3 Delta mutant and molecular mechanism exploration based on the metabolic flux and transcriptomics approaches
Saccharomyces cerevisiae generally consumes glucose to produce ethanol accompanied by the main by-products of glycerol, acetic acid, and lactic acid. The minimization of the formation of by-products in S. cerevis...
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Article
Nonlinear electronic and ultrafast optical signatures in chemical vapor-deposited ultrathin PtS2 ribbons
The emerging two-dimensional (2D) platinum disulfide (PtS2) has driven increasing attentions due to its high electron mobility, good air-stability, and strong interlayer interaction which leads to a widely tunabl...
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Article
Optimization of Initial Cation Concentrations for L-Lactic Acid Production from Fructose by Lactobacillus pentosus Cells
In this study, Box-Behnken design was applied to optimize the initial concentrations of 4 cations for L-lactic acid production from fructose by homologous batch fermentation of Lactobacillus pentosus cells. The o...
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Article
Scalable salt-templated directed synthesis of high-quality MoS2 nanosheets powders towards energetic and environmental applications
Two-dimensional (2D) transition metal dichalcogenides (TMDCs) have emerged as perfect platforms for develo** applications in nano-electronics, catalysis, energy storage and environmental-related fields due t...
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Article
Optimization of immobilization conditions for Lactobacillus pentosus cells
In this study, the immobilization technology was used to improve the LA yield and shorten the fermentation time. The optimum conditions to immobilize Lactobacillus pentosus ATCC 8041 cell were determined by Taguc...
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Article
Salt-assisted growth and ultrafast photocarrier dynamics of large-sized monolayer ReSe2
Owing to its anisotropic optical and electrical properties, rhenium diselenide (ReSe2) has garnered considerable attention recently as a candidate material for polarization-sensitive photodetectors. However, the ...
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Article
Micro or nano: Evaluation of biosafety and biopotency of magnesium metal organic framework-74 with different particle sizes
In recent years, various particulate materials have played important roles in medical applications. However, nano- and micron-sized particles of the same material could exhibit distinct properties due to diffe...
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Article
Effects of mixed cultures of Candida tropicalis and aromatizing yeast in alcoholic fermentation on the quality of apple vinegar
There are two steps (alcoholic fermentation and acetic acid fermentation) in the production of fruit vinegar by liquid fermentation. The yeast alcoholic fermentation step plays an important role in the quality...
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Article
Effects of High Hydrostatic Pressure on the Properties of Heat-Induced Wheat Gluten Gels
This study examined the effects of high hydrostatic pressure pretreatment (100–400 MPa) on the properties of heat-induced wheat gluten (WG) gels. The results showed that treatment with pressure higher than 100...
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Article
Space-confined growth of monolayer ReSe2 under a graphene layer on Au foils
Vertical heterostructures based on two-dimensional (2D) materials have attracted widespread interest for their numerous applications in electronic and optoelectronic devices. Herein, we report the direct const...
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Article
Valorization of humins by phosphoric acid activation for activated carbon production
Humins, the solid wastes from biomass acid hydrolysis, were value-added applied for activated carbon production through the phosphoric acid activation method with pyrolysis temperature ranging from 300 to 700 ...
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Article
Producing Acetic Acid of Acetobacter pasteurianus by Fermentation Characteristics and Metabolic Flux Analysis
The acetic acid bacterium Acetobacter pasteurianus plays an important role in acetic acid fermentation, which involves oxidation of ethanol to acetic acid through the ethanol respiratory chain under specific cond...
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Article
Heterologous signal peptides-directing secretion of Streptomyces mobaraensis transglutaminase by Bacillus subtilis
Microbial transglutaminase (MTG) from Streptomyces mobaraensis has been widely used for crosslinking proteins in order to acquire products with improved properties. To improve the yield and enable a facile and ef...
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Article
Cell regeneration and cyclic catalysis of engineered Kluyveromyces marxianus of a d-psicose-3-epimerase gene from Agrobacterium tumefaciens for d-allulose production
d-Allulose as a low-energy and special bioactive monosaccharide sugar is essential for human health. In this study, the d-psicose-3-epimerase gene (DPEase) of Agrobacterium tumefaciens was transferred into thermo...
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Article
Application of chemical vapor–deposited monolayer ReSe2 in the electrocatalytic hydrogen evolution reaction
Controlled synthesis of structurally anisotropic rhenium diselenide (ReSe2) with macroscopically uniform and strictly monolayer thickness as well as tunable domain shape/size is of great interest for electronics-...