14 Result(s)

Article

Mechanistic Investigation of Calcium Channel Regulation-Associated Genes in Pulmonary Arterial Hypertension and Signatures for Diagnosis

Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary disorder with complex causes. Calcium channel blockers have long been used in its treatment. Our study aimed to validate experimental results s...

Dongjuan Chen, Jun Yang, Ting Zhang, Xuemei Li, Qiliang **ong… in Molecular Biotechnology (2024)

Article

Simultaneous profiling of chromatin architecture and transcription in single cells

The three-dimensional structure of chromatin plays a crucial role in development and disease, both of which are associated with transcriptional changes. However, given the heterogeneity in single-cell chromati...

Jiale Qu, Jun Sun, Cai Zhao, **nyi Liu… in Nature Structural & Molecular Biology (2023)

Article

Optimization of Initial Cation Concentrations for L-Lactic Acid Production from Fructose by Lactobacillus pentosus Cells

In this study, Box-Behnken design was applied to optimize the initial concentrations of 4 cations for L-lactic acid production from fructose by homologous batch fermentation of Lactobacillus pentosus cells. The o...

Jianfei Wang, Shaoming Jiang, Jiaqi Huang… in Applied Biochemistry and Biotechnology (2021)

Article

Producing Acetic Acid of Acetobacter pasteurianus by Fermentation Characteristics and Metabolic Flux Analysis

The acetic acid bacterium Acetobacter pasteurianus plays an important role in acetic acid fermentation, which involves oxidation of ethanol to acetic acid through the ethanol respiratory chain under specific cond...

Xuefeng Wu, Hongli Yao, Qing Liu, Zhi Zheng… in Applied Biochemistry and Biotechnology (2018)

Article

Cell regeneration and cyclic catalysis of engineered Kluyveromyces marxianus of a d-psicose-3-epimerase gene from Agrobacterium tumefaciens for d-allulose production

d-Allulose as a low-energy and special bioactive monosaccharide sugar is essential for human health. In this study, the d-psicose-3-epimerase gene (DPEase) of Agrobacterium tumefaciens was transferred into thermo...

Peizhou Yang, **ngxing Zhu, Zhi Zheng… in World Journal of Microbiology and Biotechn… (2018)

Article

Production of Fumaric Acid by Bioconversion of Corncob Hydrolytes Using an Improved Rhizopus oryzae Strain

The use of microorganism fermentation for production of fumaric acid (FA), which is widely used in food, medicine, and other fields, can provide technical support for the FA industry. In this study, we aimed t...

Xuefeng Wu, Qing Liu, Yongdong Deng, **aoju Chen… in Applied Biochemistry and Biotechnology (2018)

Article

Influence of Altered NADH Metabolic Pathway on the Respiratory-deficient Mutant of Rhizopus oryzae and its L-lactate Production

Respiratory-deficient mutants of Rhizopus oryzae (R. oryzae) AS 3.3461 were acquired by ultraviolet (UV) irradiation to investigate changes in intracellular NADH metabolic pathway and its influence on the ferment...

Chang Shu, Chenchen Guo, Shuizhong Luo… in Applied Biochemistry and Biotechnology (2015)

Article

Poly(zwitterionic)protein conjugates offer increased stability without sacrificing binding affinity or bioactivity

Treatment with therapeutic proteins is an attractive approach to targeting a number of challenging diseases. Unfortunately, the native proteins themselves are often unstable in physiological conditions, reduci...

Andrew J. Keefe, Shaoyi Jiang in Nature Chemistry (2012)

Article

Production of l-lactic acid by Rhizopus oryzae using semicontinuous fermentation in bioreactor

Semicontinuous fermentation using pellets of Rhizopus oryzae has been recognized as a promising technology for l-lactic acid production. In this work, semicontinuous fermentation of R. oryzae AS 3.819 for l-lacti...

Xuefeng Wu, Shaotong Jiang, Mo Liu… in Journal of Industrial Microbiology & Biote… (2011)

Article

Screening, breeding and metabolic modulating of a strain producing succinic acid with corn straw hydrolyte

Purpose In this paper, the high yield mutant strain was expected to be obtained for the industrial bioconversion of corn straw hydrolyte to succinic acid. Methods API biochemical reactions and 16S r RNA sequence ...

**ngjiang Li, Zhi Zheng, Zhaojun Wei… in World Journal of Microbiology and Biotechn… (2009)

Article

Label-free detection of cancer biomarker candidates using surface plasmon resonance imaging

In this work, we present an antibody array for the detection of cancer biomarker candidates by a surface plasmon resonance (SPR) imaging sensor with polarization contrast. Responses from the SPR imaging sensor...

Jon Ladd, Allen D. Taylor, Marek Piliarik… in Analytical and Bioanalytical Chemistry (2009)

Article

Letter to the Editor: Assignment of the ¹H, ¹³C and ¹⁵N resonances of the Coxsackievirus and Adenovirus receptor domain 1

Shaokai Jiang, Michael Caffrey in Journal of Biomolecular NMR (2002)

Chapter

Investigation on the Structural Requirements for Binding Integrin α_IIbβ₃

Since the discovery of the cell adhesion sequence Arg-Gly-Asp (RGD) in fibronectin [1], it has been shown that the RGD sequence serves as a binding site of many adhesion proteins to integrin receptors [2]. The...

Silke Schabbert, Elsa Locardi, Ralph-Heiko Mattern… in Peptides: The Wave of the Future (2001)