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Article
Open AccessLong-term exposure to particulate air pollution and brachial artery flow-mediated dilation in the Old Order Amish
Atmospheric particulate matter (PM) has been associated with endothelial dysfunction, an early marker of cardiovascular risk. Our aim was to extend this research to a genetically homogenous, geographically sta...
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Article
Validation of a geropathology grading system for aging mouse studies
An understanding of early-onset mechanisms underlying age-related changes can be obtained by evaluating changes that precede frailty and end of life using histological characterization of age-related lesions. ...
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Article
Open AccessEvaluation of WISP1 as a candidate gene for bone mineral density in the Old Order Amish
Wnt1-inducible signaling pathway protein-1 (WISP1) is a novel target of the Wnt pathway for modulating osteogenesis and improving bone strength. However, it is not clear if genetic variants in the WISP1 region ar...
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Article
Open AccessMicrovascular endothelial dysfunction is associated with albuminuria and CKD in older adults
Impairment in glomerular endothelial function likely plays a major role in the development of albuminuria and CKD progression. Glomerular endothelial dysfunction may reflect systemic microvascular dysfunction,...
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Article
The establishment of a methadone treatment clinic for women in Tehran, Iran
In Iran women are less likely than men to use drugs, but suffer greater morbidity, are stigmatised, and are less likely to seek treatment. In 2007, we established a clinic in Tehran for drug using women. We re...
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Article
Liquid-Liquid Extraction of Palladium(II) from Hydrobromic Acid Media by Hexadecylpyridinium Bromide
A simple and rapid liquid-liquid extraction of palladium has been studied involving ion-pairing of bromocomplexes of palladium(II) with hexadecylpyridinium bromide (HDPB) dissolved in chloroform. The stoichiom...