Page
%P
-
Protocol
Protocol for Rodent Organotypic Hippocampal Slice Culture Model for Ex Vivo Monitoring of Epileptogenesis
Brain injury is one of the common causes of acquired epilepsy. Current treatments include anti-epileptic drugs that are anticonvulsant. However, around 30% of patients become resistant. Better understanding of...
-
Article
Open AccessNeuroprotective levels of IGF-1 exacerbate epileptogenesis after brain injury
Exogenous Insulin-Like Growth Factor-1 (IGF-1) is neuroprotective in animal models of brain injury, and has been considered as a potential therapeutic. Akt-mTOR and MAPK are downstream targets of IGF-1 signali...
