-
Article
Exploring gender differences in pharmacokinetics of central nervous system related medicines based on a systematic review approach
Due to the inevitable differences in physiological and/or genetic factors between genders, the possibility that differences in pharmacokinetics between genders may occur when exposed to the same dose of the sa...
-
Article
Deletion of Mixed Lineage Kinase Domain Like Pseudokinase Aggravates Chronic Alcohol-Induced Liver Injury via Increasing Apoptosis
he mixed lineage kinase domain like pseudokinase (MLKL) is known to play a protective role in non-alcoholic fatty liver disease (NAFLD) via inhibition of necroptosis pathway. However, the role of MLKL in alcoh...
-
Article
Open AccessAuthor Correction: Age-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
-
Article
Open AccessAge-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
Skeletal muscle aging results in the gradual suppression of myogenesis, leading to muscle mass loss. However, the specific role of cardiolipin in myogenesis has not been determined. This study investigated the...
-
Article
Open AccessHighly parallel and ultra-low-power probabilistic reasoning with programmable gaussian-like memory transistors
Probabilistic inference in data-driven models is promising for predicting outputs and associated confidence levels, alleviating risks arising from overconfidence. However, implementing complex computations wit...
-
Article
Open AccessLandslide susceptibility assessment of South Korea using stacking ensemble machine learning
Landslide susceptibility assessment (LSA) is a crucial indicator of landslide hazards, and its accuracy is improving with the development of artificial intelligence (AI) technology. However, the AI algorithms ...
-
Article
Open AccessHDAC5-mediated exosomal Maspin and miR-151a-3p as biomarkers for enhancing radiation treatment sensitivity in hepatocellular carcinoma
Tumor-derived exosomes are critical elements of the cell–cell communication response to various stimuli. This study aims to reveal that the histone deacetylase 5 (HDAC5) and p53 interaction upon radiation in h...
-
Article
Open AccessVascular abnormalities in fellow eyes of patients with unilateral coats’ disease
Coats’ disease is an idiopathic retinal vascular disorder, known to usually occur unilaterally; however, recent studies have highlighted vascular abnormalities in the fellow unaffected eyes. This retrospective...
-
Article
Open AccessClinical features of retinopathy after cardiopulmonary resuscitation
To evaluate the clinical patterns of retinopathy in patients who received cardiopulmonary resuscitation (CPR) using wide-field fundus photography and slit-lamp fundus examination.
-
Article
Open AccessDiscovery biomarker to optimize obeticholic acid treatment for non-alcoholic fatty liver disease
The response rate to obeticholic acid (OCA), a potential therapeutic agent for non-alcoholic fatty liver disease, is limited. This study demonstrated that upregulation of the alternative bile acid synthesis pa...
-
Article
Soft, adhesive and conductive composite for electroencephalogram signal quality improvement
Since electroencephalogram (EEG) is a very small electrical signal from the brain, it is very vulnerable to external noise or motion artifact, making it difficult to measure. Therefore, despite the excellent c...
-
Article
Open AccessFine structural characteristics of the chorionic microspheres on the egg surface of the orb web spider Trichonephila clavata
The eggs laid by the orb web spider Trichonephila clavata must overwinter in bitterly freezing and dry conditions before hatching, but there does not seem to be any protection like a compact silk case covering th...
-
Article
Open AccessProteomic analysis of zebrafish (Danio rerio) embryos exposed to benzyl benzoate
Benzyl benzoate (BB) is widely used in the food, cosmetics, agriculture, and pharmaceutical industries and is discharged into the aquatic environment via various water sources, including wastewater. Research o...
-
Article
Open AccessA new AMPK isoform mediates glucose-restriction induced longevity non-cell autonomously by promoting membrane fluidity
Dietary restriction (DR) delays aging and the onset of age-associated diseases. However, it is yet to be determined whether and how restriction of specific nutrients promote longevity. Previous genome-wide scr...
-
Article
Open AccessGenome-wide analysis of a cellular exercise model based on electrical pulse stimulation
Skeletal muscle communicates with other organs via myokines, which are secreted by muscle during exercise and exert various effects. Despite much investigation of the exercise, the underlying molecular mechani...
-
Article
Automatic sleep stages classification using multi-level fusion
Sleep efficiency is a factor that can determine a person’s healthy life. Sleep efficiency can be calculated by analyzing the results of the sleep stage classification. There have been many studies to classify ...
-
Article
Korean Guidelines for Pharmacoeconomic Evaluations: Updates in the Third Version
The first version of the pharmacoeconomic (PE) guidelines was published in South Korea in 2006. Despite its first revision in 2011, there were still ambiguities in its interpretation. Moreover, methodologies f...
-
Article
Open AccessRetropupillary Iris Fixation of an Artisan Myopia Lens for Intraocular Lens Dislocation and Aphakia in Eyes with Extremely High Myopia: A Case Series and a Literature Review
To describe the outcomes of retropupillary iris fixation of an iris claw Artisan Myopia intraocular lens (IOL), and to review literature on retropupillary iris fixation of iris claw models for myopia for the c...
-
Article
Open AccessVertically stacked, low-voltage organic ternary logic circuits including nonvolatile floating-gate memory transistors
Multi-valued logic (MVL) circuits based on heterojunction transistor (HTR) have emerged as an effective strategy for high-density information processing without increasing the circuit complexity. Herein, an or...
-
Article
Open AccessFunctional polymeric passivation-led improvement of bias stress with long-term durability of edge-rich nanoporous MoS2 thin-film transistors
Nanoporous patterning of two-dimensional materials using block copolymer lithography has drawn much attention. Lateral edge exposures made by the nanoporous patterning provide electrical and optical characteri...
