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Open AccessAuthor Correction: Age-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
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Article
Open AccessAge-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
Skeletal muscle aging results in the gradual suppression of myogenesis, leading to muscle mass loss. However, the specific role of cardiolipin in myogenesis has not been determined. This study investigated the...
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Article
Open AccessCOVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm
Sterol regulatory element binding protein-2 (SREBP-2) is activated by cytokines or pathogen, such as virus or bacteria, but its association with diminished cholesterol levels in COVID-19 patients is unknown. H...
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Article
Open AccessHydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3β activities
Epithelial-mesenchymal transition (EMT) occurs in the tumor microenvironment and presents an important mechanism of tumor cell intravasation, stemness acquisition, and metastasis. During metastasis, tumor cell...
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Article
Open AccessRetrospective observation on contribution and limitations of screening for breast cancer with mammography in Korea: detection rate of breast cancer and incidence rate of interval cancer of the breast
The purpose of this study was to determine the benefits and limitations of screening for breast cancer using mammography.
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Article
Open AccessThe role of the addition of ovarian suppression to tamoxifen in young women with hormone-sensitive breast cancer who remain premenopausal or regain menstruation after chemotherapy (ASTRRA): study protocol for a randomized controlled trial and progress
Ovarian function suppression (OFS) has been shown to be effective as adjuvant endocrine therapy in premenopausal women with hormone receptor-positive breast cancer. However, it is currently unclear if addition...
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Article
A proposal for a new classification of T4 breast cancer as stage IIIC: a report from the Korean Breast Cancer Society
The objective of this study is to investigate staging system of the stage IIIB and stage IIIC Breast cancer and determine the criteria for an update of the classification system. Since AJCC 6th edition, it is ...
