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Article
Extratemporal hypometabolism on FDG PET in temporal lobe epilepsy as a predictor of seizure outcome after temporal lobectomy
We investigated the relationship between the presence of extratemporal hypometabolism on fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET) and seizure outcome after temporal lobectomy in pa...
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Article
Perfusion abnormality of the caudate nucleus in patients with paroxysmal kinesigenic choreoathetosis
Previous cerebral blood flow and glucose metabolism studies suggest that the basal ganglia or thalamus is involved in the pathogenesis of paroxysmal kinesigenic choreoathetosis (PKC). However, the underlying c...
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Article
Effect of lamotrigine on cerebral blood flow in patients with idiopathic generalised epilepsy
The purpose of this study was to investigate the effects of the new anti-epileptic drug, lamotrigine, on cerebral blood flow by performing 99mTc-ethylcysteinate dimer (ECD) single-photon emission computed tomogra...
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Article
Abstracts for the 6th Congress of Asian Sleep Research Society
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Article
Cerebral blood flow abnormalities in patients with neurally mediated syncope
The aim of this study is to investigate regional cerebral blood flow (rCBF) in patients with syncope. We compared brain single photon emission computed tomography (SPECT) images of neurally mediated syncope pa...
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Article
Evaluation of Algorithms for Intracranial EEG (iEEG) Source Imaging of Extended Sources: Feasibility of Using iEEG Source Imaging for Localizing Epileptogenic Zones in Secondary Generalized Epilepsy
Precise identification of epileptogenic zones in patients with intractable drug-resistant epilepsy is critical for successful epilepsy surgery. Numerous source-imaging algorithms for localizing epileptogenic z...
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Article
Functional neuroimaging findings in patients with lateral and mesio-lateral temporal lobe epilepsy; FDG-PET and ictal SPECT studies
The differentiation of combined mesial and lateral temporal onset of seizures (mesio-lateral TLE, MLTLE) from lateral TLE (LTLE) is critical to achieve good surgical outcomes. However, the functional neuroimag...
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Article
Morphological alterations in amygdalo-hippocampal substructures in narcolepsy patients with cataplexy
Although the role of hypocretin-mediated amygdalo-hippocampal dysfunction is hypothesized to be linked with narcolepsy, there have been no human MRI studies investigating the relationship between their regiona...
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Article
A five-year longitudinal study reveals progressive cortical thinning in narcolepsy and faster cortical thinning in relation to early-onset
Narcolepsy with cataplexy is characterized by excessive daytime sleepiness, cataplexy, and other REM sleep phenomena. Previous MRI studies were cross-sectional in design and could not adequately address if dis...
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Chapter
SISCOM (Subtraction Ictal SPECT with Coregistration to MRI)
Brain single-photon emission computed tomography (SPECT) is a functional nuclear imaging technique that can provide a regional map of cerebral blood flow (CBF) changes during the interictal or ictal period in ...
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Chapter
Psychosis in Epilepsy
Psychosis develops in 2–7% of people with epilepsy (PWE). Psychotic syndromes in PWE have traditionally been classified according to their temporal relationship to seizure events: ictal, postictal, and interic...