99 Result(s)
within
Seong-** Yu
English
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessPeroxiredoxin 1 inhibits streptozotocin-induced Alzheimer’s disease-like pathology in hippocampal neuronal cells via the blocking of Ca2+/Calpain/Cdk5-mediated mitochondrial fragmentation
Oxidative stress plays an essential role in the progression of Alzheimer’s disease (AD), the most common age-related neurodegenerative disorder. Streptozotocin (STZ)-induced abnormal brain insulin signaling an...
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Open AccessUrine metabolomics unravel the effects of short-term dietary interventions on oxidative stress and inflammation: a randomized controlled crossover trial
Dietary biomarkers in urine remain elusive when evaluating diet-induced oxidative stress and inflammation. In our previous study, we conducted a randomized controlled crossover trial to compare the short-term ...
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Open AccessPreoperative smoking and robot-assisted radical cystectomy outcomes & complications in multicenter KORARC database
To investigate the influence of preoperative smoking history on the survival outcomes and complications in a cohort from a large multicenter database. Many patients who undergo radical cystectomy (RC) have a h...
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Open AccessNomogram for predicting in-hospital mortality in trauma patients undergoing resuscitative endovascular balloon occlusion of the aorta: a retrospective multicenter study
Recently, resuscitative endovascular balloon occlusion of the aorta (REBOA) had been introduced as an innovative procedure for severe hemorrhage in the abdomen or pelvis. We aimed to investigate risk factors a...
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Open AccessPIBF1 regulates trophoblast syncytialization and promotes cardiovascular development
Proper placental development in early pregnancy ensures a positive outcome later on. The developmental relationship between the placenta and embryonic organs, such as the heart, is crucial for a normal pregnan...
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Open AccessUnraveling the role of the mitochondrial one-carbon pathway in undifferentiated thyroid cancer by multi-omics analyses
The role of the serine/glycine metabolic pathway (SGP) has recently been demonstrated in tumors; however, the pathological relevance of the SGP in thyroid cancer remains unexplored. Here, we perform metabolomi...
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Open AccessMigraine is associated with the development of adult patients with inflammatory bowel disease: a nationwide, population-based study
It has been reported that migraine is more common in patients with inflammatory bowel disease (IBD) than in general. However, the impact of migraine on the development of IBD has not yet been elucidated. The a...
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Open AccessPosition error-free control of magnetic domain-wall devices via spin-orbit torque modulation
Magnetic domain-wall devices such as racetrack memory and domain-wall shift registers facilitate massive data storage as hard disk drives with low power portability as flash memory devices. The key issue to be...
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Open AccessPredictors of in-hospital mortality after successful weaning of venoarterial extracorporeal membrane oxygenation in cardiogenic shock
Limited knowledge exists regarding the predictors of mortality after successful weaning of venoarterial extracorporeal membrane oxygenation (ECMO). We aimed to identify predictors of in-hospital mortality in p...
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Open AccessImpact of decreased levels of total CO2 on in-hospital mortality in patients with COVID-19
Decreased total CO2 (tCO2) is significantly associated with all-cause mortality in critically ill patients. Because of a lack of data to evaluate the impact of tCO2 in patients with COVID-19, we assessed the impa...
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Open AccessRegulation of psoriasis, colitis, and the intestinal microbiota by clusterin
Psoriasis, a chronic and systemic inflammatory disorder characterized by activation of the interleukin (IL)-23/IL-17 axis, may be associated with the intestinal microbiota through the so-called “gut–skin axis....
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Open AccessNear-lifespan longitudinal tracking of brain microvascular morphology, topology, and flow in male mice
In age-related neurodegenerative diseases, pathology often develops slowly across the lifespan. As one example, in diseases such as Alzheimer’s, vascular decline is believed to onset decades ahead of symptomol...
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Open AccessHeterologous vaccination utilizing viral vector and protein platforms confers complete protection against SFTSV
Severe fever with thrombocytopenia syndrome virus was first discovered in 2009 as the causative agent of severe fever with thrombocytopenia syndrome. Despite its potential threat to public health, no prophylac...
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Open AccessProsaposin PS18 reduces dopaminergic neurodegeneration in a 6-hydroxydopamine rat model of Parkinson’s disease
Saposin and its precursor prosaposin are endogenous proteins with neurotrophic and anti-apoptotic properties. Prosaposin or its analog prosaposin-derived 18-mer peptide (PS18) reduced neuronal damage in hippoc...
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Open AccessClinically differential diagnosis of human granulocytic anaplasmosis and severe fever with thrombocytopenia syndrome
This study analyzed HGA and SFTS in patients with suspected tick-borne infection by focusing on key differences that clinicians can easily recognize. A retrospective analysis was performed on confirmed patient...
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Open AccessGenomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis
This study aimed to find any ambiguous genetic outlier for “oligodendroglioma, IDH-mutant and 1p/19q-codeleted (O_IDH_mut)” and “astrocytoma, IDH-mutant (A_IDH_mut)” and to redefine the genetic landscape and p...
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Open AccessCirculating blood eNAMPT drives the circadian rhythms in locomotor activity and energy expenditure
Nicotinamide adenine dinucleotide (NAD+) is an essential cofactor of critical enzymes including protein deacetylase sirtuins/SIRTs and its levels in mammalian cells rely on the nicotinamide phosphoribosyltransfer...
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Open AccessCoherent consolidation of trillions of nucleations for mono-atom step-level flat surfaces
Constructing a mono-atom step-level ultra-flat material surface is challenging, especially for thin films, because it is prohibitively difficult for trillions of clusters to coherently merge. Even though a rou...
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Open AccessImplication of high variance in germplasm characteristics
The beauty of conserving germplasm is the securement of genetic resources with numerous important traits, which could be utilized whenever they need to be incorporated into current cultivars. However, it would...
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Open AccessdTMP imbalance through thymidylate 5′-phosphohydrolase activity induces apoptosis in triple-negative breast cancers
Immunotherapy has a number of advantages over traditional anti-tumor therapy but can cause severe adverse reactions due to an overactive immune system. In contrast, a novel metabolic treatment approach can ind...
