-
Article
Evaluation of pediatric rheumatologists’ approach to rituximab use: a questionnaire study
Rituximab (RTX) is a chimeric monoclonal antibody that targets the CD20 antigen on B cells and is used in various autoimmune disorders. In this study, we aimed to measure the awareness of pediatric rheumatolog...
-
Article
Evaluation of 601 children with multisystem inflammatory syndrome (Turk MISC study)
Due to its link with the 2019 coronavirus, the multisystem inflammatory syndrome in children (MISC) has garnered considerable international interest. The aim of this study, in which MISC patients were evaluate...
-
Article
Pediatric mixed connective tissue disease versus other overlap syndromes: a retrospective multicenter cohort study
Pediatric mixed connective tissue disease (MCTD) is a subgroup of overlap syndromes. We aimed to compare the characteristics and outcomes in children with MCTD and other overlap syndromes. All MCTD patients me...
-
Article
Evaluation of periodontal status and cytokine response in children with familial Mediterranean fever or systemic juvenile idiopathic arthritis
Familial Mediterranean fever (FMF) and systemic juvenile idiopathic arthritis (sJIA) are chronic inflammatory diseases and anti-inflammatory agents are used in their treatment. This study evaluates the periodo...
-
Article
Correction to: Assessment of systemic and ocular inflammation in juvenile idiopathic arthritis via choroidal vascularity index
-
Article
Assessment of systemic and ocular inflammation in juvenile idiopathic arthritis via choroidal vascularity index
We aimed to evaluate the retina and the choroid in children with juvenile idiopathic arthritis (JIA) employing optical coherence tomography (OCT). This cross-sectional study, carried out between June 2017–Dece...
-
Article
The pyrin inflammasome aggravates inflammatory cell migration in patients with familial Mediterranean fever
Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by pathogenic variants of the MEFV gene, which encodes pyrin. Leukocyte migration to serosal sites is a key event during inflammation in FM...
-
Article
Spinal involvement in juvenile idiopathic arthritis: what do we miss without imaging?
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood. Enthesitis-related arthritis (ERA) has been one of the most controversial subtypes of JIA with a higher risk of ax...
-
Article
Comparison of IVIG resistance predictive models in Kawasaki disease
We aimed to compare the ten different scores (by Kobayashi, Egami, Harada, Formosa, Sano, Piram et al., Wu et al., Yang et al., Tan et al., and Kanai et al.) to assess their performance in predicting IVIG resi...
-
Article
Galectin-3: a new biomarker for differentiating periodic fever, adenitis, pharyngitis, aphthous stomatitis (PFAPA) syndrome from familial Mediterranean fever?
Differentiating PFAPA (periodic fever, aphthosis, pharyngitis, and adenitis) syndrome from familial Mediterranean fever (FMF) could be challenging in some cases. Galectin-3 is a lectin with regulatory function...
-
Article
Juvenile idiopathic arthritis: lymphocyte activation gene-3 is a central immune receptor in children with oligoarticular subtypes
We investigated the role of inhibitory receptors (IRs) and especially lymphocyte activation gene-3 (LAG-3) in the pathogenesis of oligoarticular juvenile idiopathic arthritis (o-JIA).
-
Article
Open AccessFrequency of juvenile idiopathic arthritis and associated uveitis in pediatric rheumatology clinics in Turkey: A retrospective study, JUPITER
Juvenile idiopathic arthritis (JIA), is the most common pediatric rheumatologic disorder with unknown etiology. Currently, no population-based data are available regarding the distribution of categories and fr...
-
Article
Performances of the “MS-score” And “HScore” in the diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis patients
Macrophage activation syndrome (MAS) is a devastating complication of systemic JIA (sJIA), seen in approximately 10–25% of the sJIA patients. A number of criteria have been proposed to differentiate between ac...
-
Article
Kawasaki-like disease in children with COVID-19
Children with Coronavirus disease 2019 (COVID-19) are being reported to have manifestations of hyperinflammatory states and/or Kawasaki-like disease. In this study, we investigated children with typical and at...
-
Article
Clusters in Pediatric Rheumatic Diseases
Rheumatic diseases usually have very diverse and complex pathophysiology resulting in different clinical phenotypes. Some certain phenotypes cluster together with a common presentation, course, and outcome. Ou...
-
Article
Open AccessChoroidal vascularity index as a biomarker of systemic inflammation in childhood Polyarteritis Nodosa and adenosine deaminase-2 deficiency
To assess EDI-OCT (enhanced depth imaging optical coherence tomography) of choroid for inflammatory signs in children with polyarteritis nodosa (PAN) and adenosine deaminase-2 deficiency (DADA-2).
-
Article
Open AccessPleural effusion as an atypical presentation of Kawasaki disease: a case report and review of the literature
Kawasaki disease is an acute, febrile vasculitis of childhood that affects medium-sized arteries, predominantly the coronary arteries. It is a multisystem disease; therefore, it may present with non-cardiac fi...
-
Article
The factors affecting the disease course in Kawasaki disease
The aim of this study was to review the characteristics of patients with Kawasaki disease (KD) from Turkey and to assess the performance of the Kobayashi score (KS), Harada score (HS), Formosa score (FS), Egam...
-
Article
Is age associated with disease severity and compliance to treatment in children with familial Mediterranean fever?
Familial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disease in the world. The disease characteristics may vary in different age groups. In this study, we aimed to compare disease c...
-
Chapter
Familial Mediterranean Fever
Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disease which has a high prevalence in the eastern Mediterranean. The typical FMF attack is characterized by fever and polyserositis in the fo...
