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  1. Article

    Open Access

    Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine

    Innate lymphoid cells (ILC), including natural killer (NK) cells, are implicated in host-defense and tissue-growth. However, the composition and kinetics of NK cells in the intestine during the first year of l...

    Adrian F. Sagebiel, Fenja Steinert, Sebastian Lunemann in Nature Communications (2019)

  2. Article

    Open Access

    Hobit expression by a subset of human liver-resident CD56bright Natural Killer cells

    Immune responses show a high degree of tissue specificity shaped by factors influencing tissue egress and retention of immune cells. The transcription factor Hobit was recently shown to regulate tissue-residen...

    Sebastian Lunemann, Gloria Martrus, Hanna Goebels, Tobias Kautz in Scientific Reports (2017)

  3. Article

    Open Access

    Peptide-specific engagement of the activating NK cell receptor KIR2DS1

    The activating NK cell receptor KIR2DS1 has been shown to be involved in many disorders including autoimmune diseases, malignancies and pregnancy outcomes. However, the precise ligands and functions of this re...

    Anaïs Chapel, Wilfredo F. Garcia-Beltran, Angelique Hölzemer in Scientific Reports (2017)

  4. No Access

    Chapter

    Immunopathogenesis of Hepatitis D

    Infection with the hepatitis D virus (HDV) causes hepatitis delta, which is considered to be the most severe form of viral hepatitis. HDV is a defective virus, using the hepatitis B virus (HBV) surface antigen...

    Sebastian Lunemann, Jan Grabowski, Heiner Wedemeyer in Liver Immunology (2014)