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  1. No Access

    Chapter

    Lung Cancer

    The accurate diagnosis, staging and management of lung cancer occupies a large part of modern adult respiratory practice. Although smoking is less prevalent, the incidence and mortality of this condition remai...

    Seamus Grundy, Rachael Barton, Anne Campbell… in Foundations of Respiratory Medicine (2018)

  2. Article

    Open Access

    Additive anti-inflammatory effects of corticosteroids and phosphodiesterase-4 inhibitors in COPD CD8 cells

    CD8 lymphocytes play an important role in the pathogenesis of COPD. Corticosteroids and phosphodiesterase 4 (PDE4) inhibitors are anti-inflammatory drugs used for COPD treatment. Little is known of the combine...

    Seamus Grundy, Jonathan Plumb, Manminder Kaur, David Ray… in Respiratory Research (2016)

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  3. No Access

    Chapter

    Thoracoscopy for Spontaneous Pneumothorax

    Spontaneous pneumothorax is a relatively common disease with an incidence for primary spontaneous pneumothorax (PSP) of 18–28/100,000 per year in males and 1.8–6/100,000 per year in females (Henry et al. 2003)...

    Seamus Grundy, Andrew Bentley in Thoracoscopy for Pulmonologists (2014)

  4. Article

    Open Access

    T lymphocyte insensitivity to corticosteroids in chronic obstructive pulmonary disease

    There are increased numbers of activated lymphocytes in the lungs of chronic obstructive pulmonary disease (COPD) patients. The clinical benefits of corticosteroids in COPD patients are limited. Our hypothesis...

    Manminder Kaur, Lucy JC Smyth, Paul Cadden, Seamus Grundy… in Respiratory Research (2012)

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