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Article
Open AccessStudy protocol for a randomized controlled trial with rituximab for psychotic disorder in adults (RCT-Rits)
The role of inflammation in the aetiology of schizophrenia has gained wide attention and research on the association shows an exponential growth in the last 15 years. Autoimmune diseases and severe infections ...
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Article
Open AccessDiagnostic spirometry in COPD is increasing, a comparison of two Swedish cohorts
Spirometry should be used to confirm a diagnosis of chronic obstructive pulmonary disease (COPD). This test is not always performed, leading to possible misdiagnosis. We investigated whether the proportion of ...
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Article
Open AccessDoes multimorbidity result in de-prioritisation of COPD in primary care?
The aim of this study was to describe factors associated with having COPD regularly reviewed in primary care by a nurse or physician and assess whether there was de-prioritisation for COPD in multimorbid patie...
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Article
Neuroticism and Sexual Orientation-Based Victimization as Mediators of Sexual Orientation Disparities in Mental Health
This study tested whether elevated risk of poorer mental health outcomes among nonheterosexual adolescents compared with heterosexual adolescents is plausibly explained by neuroticism and sexual orientation-ba...
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Article
Open AccessValidity of Routinely Collected Swedish Data in the International Enhanced Recovery After Surgery (ERAS) Database
This study aims to assess patient coverage, validity and data quality in the Swedish part of the International Enhanced Recovery After Surgery (ERAS) Interactive Audit System (EIAS).
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Article
Open AccessSex differences in associations of fine particulate matter with non-accidental deaths: an ecological time-series study
Sex differences in the impact of exposure to air pollution have been reported previously and epidemiological studies indicate that fine particulate matter (PM2.5) effects on nonaccidental death are modified by se...
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Article
Open AccessAssociations of self-reported atopic dermatitis with comorbid conditions in adults: a population-based cross-sectional study
The objective of this study was to investigate the relationships between atopic dermatitis (AD) and other common chronic health conditions in adults.
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Article
Open AccessThe statistical importance of P-POSSUM scores for predicting mortality after emergency laparotomy in geriatric patients
Geriatric patients frequently undergo emergency general surgery and accrue a greater risk of postoperative complications and fatal outcomes than the general population. It is highly relevant to develop the mos...
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Article
Open AccessData-driven questionnaire-based cluster analysis of asthma in Swedish adults
The aim of this study was to identify asthma phenotypes through cluster analysis. Cluster analysis was performed using self-reported characteristics from a cohort of 1291 Swedish asthma patients. Disease burde...
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Article
Open AccessBeta-blockeRs tO patieNts with CHronIc Obstructive puLmonary diseasE (BRONCHIOLE) – Study protocol from a randomized controlled trial
Observational studies indicate that beta-blockers are associated with a reduced risk of exacerbation and mortality in patients with chronic obstructive pulmonary disease (COPD) even without overt cardiovascula...
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Article
Open AccessEvaluation of SPP1/osteopontin expression as predictor of recurrence in tamoxifen treated breast cancer
Breast cancer patients treated with tamoxifen may experience recurrence due to endocrine resistance, which highlights the need for additional predictive and prognostic biomarkers. The glyco-phosphoprotein oste...
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Article
Open AccessChanging diagnostic criteria for gestational diabetes in Sweden - a stepped wedge national cluster randomised controlled trial - the CDC4G study protocol
The optimal criteria to diagnose gestational diabetes mellitus (GDM) remain contested. The Swedish National Board of Health introduced the 2013 WHO criteria in 2015 as a recommendation for initiation of treatm...
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Article
Open AccessOpium use during pregnancy and infant size at birth: a cohort study
The reported positive association between opiatic drug use during pregnancy and adverse pregnancy outcomes might be confounded by other factors related to high-risk behaviors, including the use of other harmfu...
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Article
Open AccessSex Hormones, Gonadotropins, and Sex Hormone-binding Globulin in Infants Fed Breast Milk, Cow Milk Formula, or Soy Formula
Measurement of endogenous hormones in early life is important to investigate the effects of hormonally active environmental compounds. To assess the possible hormonal effects of different feeding regimens in d...
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Article
Open AccessChange in health status in COPD: a seven-year follow-up cohort study
Health status is a prognostic factor included in the assessment of chronic obstructive pulmonary disease (COPD). The aim of our study was to examine the associations of clinical factors with change in health s...
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Article
Open AccessNo signs of dose escalations of potent opioids prescribed after tibial shaft fractures: a study of Swedish National Registries
The pattern of opioid use after skeletal trauma is a neglected topic in pain medicine. The purpose of this study was to analyse the long-term prescriptions of potent opioids among patients with tibial shaft fr...
